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Active Recombinant Human IL1RL2 protein, His-tagged

Cat.No. : IL1RL2-1009H
Product Overview : Recombinant Human IL1RL2 protein(Asp 20 - Arg 335 ), fused with His tag, was expressed in HEK293.
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  • Gene Information
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Source : HEK293
Species : Human
Tag : His
Form : Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally trehalose is added as protectant before lyophilization.
Bio-activity : Immobilized Anti-IL36R Antibody, Human IgG1 at 1 μg/mL (100 μL/well) can bind Human IL-1 Rrp2 (C154S, C262S) Protein, His Tag with a linear range of 4-125 ng/mL.Immobilized Human IL-1 Rrp2 (C154S, C262S) Protein, His Tag at 1 μg/mL (100 μL/well) can bind Anti-Human IL-1 Rrp2 MAb, Human IgG with a linear range of 0.2-3 ng/mL.
Molecular Mass : This protein carries a polyhistidine tag at the C-terminus.The protein has a calculated MW of 37.9 kDa. The protein migrates as 55-65 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Proteinlength : Asp20-Arg335
Endotoxin : Less than 1.0 EU per μg by the LAL method.
Purity : >95% as determined by SDS-PAGE.>90% as determined by SEC-MALS.
Storage : For long term, the product should be stored at lyophilized state at -20°C or lower.Please avoid repeated freeze-thaw cycles. This product is stable after at:
-20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution.
Reconstitution : It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents.
Gene Name : IL1RL2 interleukin 1 receptor-like 2 [ Homo sapiens ]
Official Symbol : IL1RL2
Synonyms : IL1RL2; interleukin 1 receptor-like 2; interleukin-1 receptor-like 2; IL1R rp2; IL1RRP2; IL-1Rrp2; interleukin-1 receptor-related protein 2; IL1R-rp2;
Gene ID : 8808
mRNA Refseq : NM_003854
Protein Refseq : NP_003845
MIM : 604512
UniProt ID : Q9HB29

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (10)

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What is the role of Il1rl2 in cardiac hypertrophy? 05/10/2020

Il1rl2 is involved in the development of cardiac hypertrophy.

How does Il1rl2 expression change in response to bacterial infection? 01/01/2019

Il1rl2 expression is upregulated in response to bacterial infection.

How does Il1rl2 affect macrophage polarization? 12/21/2018

Il1rl2 induces M2 macrophage polarization.

What is the affinity of Il1rl2 for its primary ligand? 09/08/2018

Il1rl2 has high affinity for its primary ligand, IL-36.

What is the role of Il1rl2 in adipogenesis? 05/14/2018

Il1rl2 promotes adipogenesis by activating PPAR-gamma.

What is the half-life of Il1rl2 in serum? 05/11/2018

The half-life of Il1rl2 in serum is approximately 30 minutes.

Does Il1rl2 interact with any membrane receptors? 03/15/2018

Il1rl2 interacts with IL-36R on the cell membrane.

Does Il1rl2 undergo post-translational modifications? 12/28/2017

Il1rl2 undergoes phosphorylation.

Does Il1rl2 contribute to the blood-brain barrier permeability? 12/06/2016

Il1rl2 increases blood-brain barrier permeability.

Is Il1rl2 expression influenced by circadian rhythms? 09/28/2016

Il1rl2 expression is not influenced by circadian rhythms.

Customer Reviews (3)

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Reviews
11/17/2022

    High purity.

    03/07/2019

      Good for receptor binding.

      10/14/2018

        Effective in inflammation assays.

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