Recombinant Human IL1RL2 protein, His-Avi-tagged

• Cat.No.: IL1RL2-929H
• Product Overview: Recombinant Human IL-1 Rrp2/IL-1 R6 Protein is expressed from mammalian with His and Avi Tag at the C-terminal. It contains Asp 20-Arg 335.

Specification

• Description: The Interleukin 1 receptor family (IL-1 R) comprises at least eleven members including IL-1 RI (IL-1 R1), IL-1 RII (IL-1 R2), IL-1 RAcP (IL‑1 R3), ST2 (T1/IL-1 R4), IL-18 Ra (IL-1 Rrp/IL-1 R5), IL-1 Rrp2 (IL-1 RL2/IL-1 R6), IL-18 Rb (AcPL/IL-1 R7), IL-1RAPL‑1 (TIGIRR‑2/IL‑1 R8), and TIGIRR-1 (IL-1 R9). IL1RL2 is a receptor for interleukin-36 (IL36A, IL36B and IL36G). After binding to interleukin-36 associates with the coreceptor IL1RAP to form the interleukin-36 receptor complex which mediates interleukin-36-dependent activation of NF-kappa-B, MAPK and other pathways.
• Source: HEK293
• Species: Human
• Tag: His-Avi
• Form: Supplied as 0.22um filtered solution in PBS (pH 7.4).
• Molecular Mass: The protein has a predicted MW of 39.1 kDa. Due to glycosylation, the protein migrates to 60-80KDa based on Bis-Tris PAGE result.
• Protein length: Asp 20-Arg 335
• Endotoxin: Less than 0.1EU per ug by the LAL method.
• Purity: > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
• Storage: The product should be stored at -70°C. Please do not repeated freeze-thaw cycles.

Gene Information

• Gene Name: IL1RL2 interleukin 1 receptor like 2 [ Homo sapiens (human) ]
• Official Symbol: IL1RL2
• Synonyms: IL-1 R6; IL-1 Rrp2; IL1RL2; IL-1RL2; IL1Rrp2; IL-1Rrp2; IL1RRP2IL1R-rp2Interleukin-1 receptor-related protein 2; interleukin 1 receptor-like 2; interleukin-1 receptor-like 2
• Gene ID: 8808
• mRNA Refseq: NM_001351446.2
• Protein Refseq: NP_001338375.1
• MIM: 604512
• UniProt ID: Q9HB29