Recombinant Human IL1RN, His-tagged
| Cat.No. : | IL1RN-28733TH |
| Product Overview : | Recombinant fusion protein, corresponding to amino acids 26-177 of Human IL1RA (152 amino acids) with an N terminal hexahistidine tag. |
- Specification
- Gene Information
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| Description : | The protein encoded by this gene is a member of the interleukin 1 cytokine family. This protein inhibits the activities of interleukin 1, alpha (IL1A) and interleukin 1, beta (IL1B), and modulates a variety of interleukin 1 related immune and inflammatory responses. This gene and five other closely related cytokine genes form a gene cluster spanning approximately 400 kb on chromosome 2. A polymorphism of this gene is reported to be associated with increased risk of osteoporotic fractures and gastric cancer. Four alternatively spliced transcript variants encoding distinct isoforms have been reported. |
| Conjugation : | HIS |
| Source : | E. coli |
| Tissue specificity : | The intracellular form of IL1RN is predominantly expressed in epithelial cells. |
| Form : | Liquid |
| Purity : | >95% by SDS-PAGE |
| Storage : | Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. |
| Gene Name : | IL1RN interleukin 1 receptor antagonist [ Homo sapiens ] |
| Official Symbol : | IL1RN |
| Synonyms : | IL1RN; interleukin 1 receptor antagonist; interleukin-1 receptor antagonist protein; ICIL 1RA; IL 1RN; IL1F3; IL1RA; interleukin 1 receptor antagonist protein; intracellular interleukin 1 receptor antagonist; IRAP; MGC10430; |
| Gene ID : | 3557 |
| mRNA Refseq : | NM_000577 |
| Protein Refseq : | NP_000568 |
| MIM : | 147679 |
| Uniprot ID : | P18510 |
| Chromosome Location : | 2q14.2 |
| Pathway : | Cytokine Signaling in Immune system, organism-specific biosystem; IL-1 Signaling Pathway, organism-specific biosystem; IL1-mediated signaling events, organism-specific biosystem; Immune System, organism-specific biosystem; Interleukin-1 signaling, organism-specific biosystem; |
| Function : | interleukin-1 Type I receptor antagonist activity; interleukin-1 Type II receptor antagonist activity; interleukin-1 receptor antagonist activity; interleukin-1 receptor antagonist activity; interleukin-1 receptor binding; |
Products Types
| ◆ Recombinant Protein | ||
| IL1RN-4363R | Recombinant Rabbit IL1RN Protein | +Inquiry |
| IL1RN-1819H | Recombinant Human IL1RN Protein, MYC/DDK-tagged | +Inquiry |
| IL1RN-183I | Active Recombinant Human IL1RN Protein | +Inquiry |
| IL1RN-167H | Recombinant Active Human IL1RN Protein, His-tagged(C-ter) | +Inquiry |
| IL1RN-164H | Active Recombinant Human IL1RN Protein (Arg26-Glu177), C-His tagged, Animal-free, Carrier-free | +Inquiry |
| ◆ Lysates | ||
| IL1RN-1375RCL | Recombinant Rat IL1RN cell lysate | +Inquiry |
| IL1RN-2912HCL | Recombinant Human IL1RN cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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