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Recombinant Human IL22, GST-tagged

Cat.No. : IL22-14185H
Product Overview : Recombinant Human IL22 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.
Availability February 17, 2025
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Source : E.coli
Species : Human
Tag : GST
Protein length : 28-179a.a.
Storage : The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
Storage Buffer : 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.
Gene Name : IL22 interleukin 22 [ Homo sapiens ]
Official Symbol : IL22
Synonyms : IL22; interleukin 22; interleukin-22; IL 10 related T cell derived inducible factor; IL 21; IL 22; IL D110; IL TIF; ILTIF; MGC79382; MGC79384; TIFa; TIFIL 23; zcyto18; cytokine Zcyto18; IL-10-related T-cell-derived inducible factor; IL-10-related T-cell-derived-inducible factor; IL-21; IL-22; IL-TIF; IL-D110; TIFIL-23;
Gene ID : 50616
mRNA Refseq : NM_020525
Protein Refseq : NP_065386
MIM : 605330
UniProt ID : Q9GZX6
Chromosome Location : 12q15
Pathway : Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; Jak-STAT signaling pathway, organism-specific biosystem; Jak-STAT signaling pathway, conserved biosystem;
Function : cytokine activity; interleukin-22 receptor binding;

Not For Human Consumption!

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Customer Reviews (3)

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Reviews
04/07/2021

    High specificity.

    03/29/2021

      Good for Th17 differentiation.

      07/07/2016

        Effective in gut repair assays.

        Q&As (10)

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        What is IL22's role in gut epithelial repair? 02/05/2022

        IL22 enhances gut epithelial repair mechanisms.

        What are the downstream targets of IL22 signaling? 12/27/2021

        IL22 activates STAT3 to modulate downstream targets.

        How does IL22 interact with other cytokines in inflammation? 10/06/2021

        IL22 interacts synergistically with IL-17 during inflammation.

        Is IL22 involved in the pathogenesis of autoimmune diseases? 06/25/2021

        IL22 is involved in the pathogenesis of autoimmune diseases like Crohn's.

        Does IL22 have a role in metabolic syndrome? 02/23/2021

        IL22 is implicated in metabolic syndrome by affecting insulin sensitivity.

        How is IL22 expression regulated in psoriasis? 09/05/2018

        IL22 expression is upregulated in psoriasis.

        Does IL22 expression change during viral infections? 07/26/2018

        IL22 expression is upregulated during viral infections like Hepatitis C.

        Does IL22 contribute to anti-tumor immunity? 03/14/2018

        IL22 contributes to anti-tumor immunity by activating NK cells.

        How does IL22 modulate T-cell differentiation? 10/30/2017

        IL22 promotes Th22 cell differentiation.

        What impact do IL22 polymorphisms have on its function? 09/25/2017

        IL22 polymorphisms affect its binding affinity and signaling.

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