Recombinant Human IL22 Protein
|Product Overview :||Recombinant human IL22 protein|
- Gene Information
- Related Products
|Description :||This gene is a member of the IL10 family of cytokines that mediate cellular inflammatory responses. The encoded protein functions in antimicrobial defense at mucosal surfaces and in tissue repair. This protein also has pro-inflammatory properties and plays a role in in the pathogenesis of several intestinal diseases. The encoded protein is a crucial cytokine that regulates host immunity in infectious diseases, including COVID-19 (disease caused by SARS-CoV-2).|
|Protein Length :||179|
|AA Sequence :||MAALQKSVSSFLMGTLATSCLLLLA LLVQGGAAAPISSHCRLDKSNFQQP YITNRTFMLAKEASLADNNTDVRLI GEKLFHGVSMSERCYLMKQVLNFTL EEVLFPQSDRFQPYMQEVVPFLARL SNRLSTCHIEGDDLHIQRNVQKLKD TVKKLGESGEIKAIGELDLLFMSLR NACI|
|Purity :||> 98%|
|Applications :||WB; ELISA; FACS; FC|
|Stability :||This bioreagent is stable at 4 centigrade (short-term) and -70 centigrade(long-term). After reconstitution, sample may be stored at 4 centigrade for 2-7 days and below -18 centigrade for future use.|
|Storage :||At -20 centigrade.|
|Storage Buffer :||PBS (pH 7.4-7.5). Sterile-filtered colorless solution.|
|Reconstitution :||Reconstitute in sterile distilled H2O to no less than 100 μg/mL; dilute reconstituted stock further in other aqueous solutions if needed. Please review COA for lot-specific instructions. Final measurements should be determined by the end-user for optimal performance.|
|Gene Name :||IL22 interleukin 22 [ Homo sapiens (human) ]|
|Official Symbol :||IL22|
|Synonyms :||IL22; interleukin 22; interleukin-22; IL 10 related T cell derived inducible factor; IL 21; IL 22; IL D110; IL TIF; ILTIF; MGC79382; MGC79384; TIFa; TIFIL 23; zcyto18; cytokine Zcyto18; IL-10-related T-cell-derived inducible factor; IL-10-related T-cell-derived-inducible factor; IL-21; IL-22; IL-TIF; IL-D110; TIFIL-23;|
|Gene ID :||50616|
|mRNA Refseq :||NM_020525|
|Protein Refseq :||NP_065386|
|UniProt ID :||Q9GZX6|
|◆ Recombinant Protein|
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Q&As (10)Ask a question
IL22 enhances gut epithelial repair mechanisms.
IL22 activates STAT3 to modulate downstream targets.
IL22 interacts synergistically with IL-17 during inflammation.
IL22 is involved in the pathogenesis of autoimmune diseases like Crohn's.
IL22 is implicated in metabolic syndrome by affecting insulin sensitivity.
IL22 expression is upregulated in psoriasis.
IL22 expression is upregulated during viral infections like Hepatitis C.
IL22 contributes to anti-tumor immunity by activating NK cells.
IL22 promotes Th22 cell differentiation.
IL22 polymorphisms affect its binding affinity and signaling.
Customer Reviews (3)Write a review
High specificity. -
Good for Th17 differentiation. -
Effective in gut repair assays. -
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