Recombinant Human IL22RA2 Protein, His-tagged

• Cat.No.: IL22RA2-2302H
• Product Overview: Recombinant Human IL22RA2 Protein (Thr22-Pro263) with a N-His tag was expressed in E. coli.

Specification

• Description: This gene encodes a member of the class II cytokine receptor family. The encoded soluble protein specifically binds to and inhibits interleukin 22 activity by blocking the interaction of interleukin 22 with its cell surface receptor. The encoded protein may be important in the regulation of inflammatory response, and has been implicated in the regulation of tumorigenesis in the colon. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
• Source: E. coli
• Species: Human
• Tag: N-His
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 31.9 kDa
  Accurate Molecular Mass: 32 kDa
• Protein length: Thr22-Pro263
• Endotoxin: <1.0 EU per 1µg (determined by the LAL method).
• Purity: > 90%
• Applications: Positive Control; Immunogen; SDS-PAGE; WB.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Storage Buffer: 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
• Reconstitution: Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.

Gene Information

• Gene Name: IL22RA2 interleukin 22 receptor, alpha 2 [ Homo sapiens (human) ]
• Official Symbol: IL22RA2
• Synonyms: IL22RA2; interleukin 22 receptor, alpha 2; interleukin-22 receptor subunit alpha-2; CRF2 S1; IL 22BP; zcytoR16; IL-22R-alpha-2; class II cytokine receptor; IL-22 receptor subunit alpha-2; interleukin 22-binding protein; interleukin-22-binding protein; cytokine receptor class-II member 10; cytokine receptor family 2 member 10; cytokine receptor family type 2, soluble 1; CRF2X; CRF2-10; CRF2-S1; IL-22BP; IL-22RA2; MGC150509; MGC150510
• Gene ID: 116379
• mRNA Refseq: NM_052962
• Protein Refseq: NP_443194
• MIM: 606648
• UniProt ID: Q969J5