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Recombinant Human IL23A Protein, Animal Free
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Cat.No. : | IL23A-32H Optional Service: Optional requirements on this protein |
Product Overview : | Recombinant Human IL23A Protein without tag was expressed in Human cells. Animal Free and Xeno Free |
Description : | IL-23 is a heterodimeric cytokine composed of two subunits: a unique p19 subunit, and a p40 subunit that is shared with IL-12. IL-23 is secreted by activated dendritic cells and macrophages. IL-23 binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the Jak-Stat signaling cascade, stimulates memory rather than naive T cells and promotes production of proinflammatory cytokines, such as IFNγ and IL-17. IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis. |
Source : | Human cells |
Species : | Human |
Bio-activity : | The activity was measured by its ability to induce the IL-17 expression in murine splenocytes. |
Molecular Mass : | 55 kDa |
Endotoxin : | <0.5 EU/ μg |
Purity : | High Purity, >95% by SDS-PAGE |
Stability : | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. In general: 12 months from date of receipt, -20 to -80 centigrade as supplied. 1 month, 2 to 8 centigrade under sterile conditions after reconstitution. 3 months, -20 to -80 centigrade under sterile conditions after reconstitution. |
Storage Buffer : | Lyophilized from a 0.2 μm filtered solution in PBS without carrier protein |
Reconstitution : | Briefly centrifuge the vial before opening. It is recommended to reconstitute the protein in sterile PBS containing 0.1% endotoxin-free recombinant human serum albumin. |
Gene Name : | IL23A interleukin 23 subunit alpha [ Homo sapiens (human) ] |
Official Symbol : | IL23A |
Synonyms : | IL23A; interleukin 23 subunit alpha; P19; SGRF; IL-23; IL-23A; IL23P19; interleukin-23 subunit alpha; IL-23 subunit alpha; IL-23-A; IL-23p19; JKA3 induced upon T-cell activation; interleukin 23 p19 subunit; interleukin 23, alpha subunit p19; interleukin-23 subunit p19; interleukin-six, G-CSF related factor |
Gene ID : | 51561 |
mRNA Refseq : | NM_016584 |
Protein Refseq : | NP_057668 |
MIM : | 605580 |
UniProt ID : | Q9H2A5 |
◆ Recombinant Protein
Il23a-3516M | Recombinant Mouse Il23a Protein, Myc/DDK-tagged | +Inquiry |
IL23A-02H | Recombinant Human Active IL23A Protein, His-tagged | +Inquiry |
IL23A-2303H | Recombinant Human IL23A Protein, His-tagged | +Inquiry |
Il23a-1927M | Recombinant Mouse Il23a Protein | +Inquiry |
IL23A-451H | Recombinant Human IL23A Protein, Fc-tagged | +Inquiry |
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◆ Lysates
IL23A-5231HCL | Recombinant Human IL23A 293 Cell Lysate | +Inquiry |
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IL10IL10RAIL10RBIL11IL11RAIl11ra1IL12IL12AIL12BIL12RB1IL13IL13RA1IL13RA2IL15IL15RAIL16IL17AIL17BIl17cIL17DIl17fIL17RAIL17RDIL18IL18BPIL18R1IL18RAPIl19Il1aIl1bIL1F10IL1R1Il1r2IL1RAPIL1RAPL1IL1RAPL2IL1RL1IL1RL2Il1rnIL2Il20IL20RAIL21IL21RIL22IL22BPIL22RA1IL22RA2IL23AIL24Il25IL27IL27RAIL28AIl28bIL29IL2RAIL2RBIl2rgIL3IL31IL32Il33Il34IL3RAIL4IL4RIl4raIl5IL5RAIl6IL6RIl6raIL6STIl7IL7RIL8IL9IL36AIl12rb2IL17RBIL23RIL26IL31RAIL36BIL36GIL36RNIL37IL9RIL17RCIL17REIL28RAIL4I1IL20RBIL17RELIl11ra2IL27bIL7RAIl23a&Il12b
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