Recombinant Human IL23A Protein, Animal Free IL23A-32H

Recombinant Human IL23A Protein, Animal Free

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Recombinant Human IL23A Protein, Animal Free

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Cat.No. : IL23A-32H Optional Service: Optional requirements on this protein
Product Overview : Recombinant Human IL23A Protein without tag was expressed in Human cells.
Animal Free and Xeno Free
Description : IL-23 is a heterodimeric cytokine composed of two subunits: a unique p19 subunit, and a p40 subunit that is shared with IL-12. IL-23 is secreted by activated dendritic cells and macrophages. IL-23 binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the Jak-Stat signaling cascade, stimulates memory rather than naive T cells and promotes production of proinflammatory cytokines, such as IFNγ and IL-17. IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis.
Source : Human cells
Species : Human
Bio-activity : The activity was measured by its ability to induce the IL-17 expression in murine splenocytes.
Molecular Mass : 55 kDa
Endotoxin : <0.5 EU/ μg
Purity : High Purity, >95% by SDS-PAGE
Stability : Use a manual defrost freezer and avoid repeated freeze-thaw cycles. In general: 12 months from date of receipt, -20 to -80 centigrade as supplied. 1 month, 2 to 8 centigrade under sterile conditions after reconstitution. 3 months, -20 to -80 centigrade under sterile conditions after reconstitution.
Storage Buffer : Lyophilized from a 0.2 μm filtered solution in PBS without carrier protein
Reconstitution : Briefly centrifuge the vial before opening. It is recommended to reconstitute the protein in sterile PBS containing 0.1% endotoxin-free recombinant human serum albumin.
Gene Name : IL23A interleukin 23 subunit alpha [ Homo sapiens (human) ]
Official Symbol : IL23A
Synonyms : IL23A; interleukin 23 subunit alpha; P19; SGRF; IL-23; IL-23A; IL23P19; interleukin-23 subunit alpha; IL-23 subunit alpha; IL-23-A; IL-23p19; JKA3 induced upon T-cell activation; interleukin 23 p19 subunit; interleukin 23, alpha subunit p19; interleukin-23 subunit p19; interleukin-six, G-CSF related factor
Gene ID : 51561
mRNA Refseq : NM_016584
Protein Refseq : NP_057668
MIM : 605580
UniProt ID : Q9H2A5
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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