Recombinant Human IL27RA Protein, Fc-tagged
| Cat.No. : | IL27RA-328H |
| Product Overview : | Recombinant human IL27RA protein with Fc tag was expressed in HEK293. |
- Specification
- Gene Information
- Related Products
| Description : | In mice, CD4+ helper T-cells differentiate into type 1 (Th1) cells, which are critical for cell-mediated immunity, predominantly under the influence of IL12. Also, IL4 influences their differentiation into type 2 (Th2) cells, which are critical for most antibody responses. Mice deficient in these cytokines, their receptors, or associated transcription factors have impaired, but are not absent of, Th1 or Th2 immune responses. This gene encodes a protein which is similar to the mouse T-cell cytokine receptor Tccr at the amino acid level, and is predicted to be a glycosylated transmembrane protein. |
| Source : | HEK293 |
| Species : | Human |
| Tag : | Fc |
| Form : | Lyophilized |
| Molecular Mass : | 79 kDa |
| Protein Length : | 636 |
| AA Sequence : | MRGGRGAPFWLWPLPKLALLPLLWV LFQRTRPQGSAGPLQCYGVGPLGDL NCSWEPLGDLGAPSELHLQSQKYRS NKTQTVAVAAGRSWVAIPREQLTMS DKLLVWGTKAGQPLWPPVFVNLETQ MKPNAPRLGPDVDFSEDDPLEATVH WAPPTWPSHKVLICQFHYRRCQEAA WTLLEPELKTIPLTPVEIQDLELAT GYKVYGRCRMEKEEDLWGEWSPILS FQTPPSAPKDVWVSGNLCGTPGGEE PLLLWKAPGPCVQVSYKVWFWVGGR ELSPEGITCCCSLIPSGAEWARVSA VNATSWEPLTNLSLVCLDSASAPRS VAVSSIAGSTELLVTWQPGPGEPLE HVVDWARDGDPLEKLNWVRLPPGNL SALLPGNFTVGVPYRITVTAVSASG LASASSVWGFREELAPLVGPTLWRL QDAPPGTPAIAWGEVPRHQLRGHLT HYTLCAQSGTSPSVCMNVSGNTQSV TLPDLPWGPCELWVTASTIAGQGPP GPILRLHLPDNTLRWKVLPGILFLW GLFLLGCGLSLATSGRCYHLRHKVL PRWVWEKVPDPANSSSGQPHMEQVP EAQPLGDLPILEVEEMEPPPVMESS QPAQATAPLDSGYEKHFLPTPEELG LLGPPRPQVLA |
| Purity : | > 98% |
| Applications : | WB; ELISA; FACS; FC |
| Stability : | This bioreagent is stable at 4 centigrade (short-term) and -70 centigrade(long-term). After reconstitution, sample may be stored at 4 centigrade for 2-7 days and below -18 centigrade for future use. |
| Storage : | At -20 centigrade. |
| Concentration : | 1 mg/mL |
| Storage Buffer : | PBS (pH 7.4-7.5). Sterile-filtered colorless solution. |
| Reconstitution : | Reconstitute in sterile distilled H2O to no less than 100 μg/mL; dilute reconstituted stock further in other aqueous solutions if needed. Please review COA for lot-specific instructions. Final measurements should be determined by the end-user for optimal performance. |
| Gene Name : | IL27RA interleukin 27 receptor, alpha [ Homo sapiens (human) ] |
| Official Symbol : | IL27RA |
| Synonyms : | IL27RA; interleukin 27 receptor, alpha; interleukin-27 receptor subunit alpha; CRL1; IL 27R; T cell cytokine receptor type 1; TCCR; WSX 1; WSX1; zcytor1; IL-27RA; IL-27R-alpha; IL-27R subunit alpha; cytokine receptor-like 1; class I cytokine receptor; IL-27 receptor subunit alpha; T-cell cytokine receptor type 1; type I T-cell cytokine receptor; IL27R; |
| Gene ID : | 9466 |
| mRNA Refseq : | NM_004843 |
| Protein Refseq : | NP_004834 |
| MIM : | 605350 |
| UniProt ID : | Q6UWB1 |
Products Types
| ◆ Recombinant Protein | ||
| IL27RA-1928H | Recombinant Human IL27RA Protein, MYC/DDK-tagged | +Inquiry |
| Il27ra-72M | Recombinant Mouse Il27ra Protein, His (Fc)-Avi-tagged | +Inquiry |
| Il27ra-3519M | Recombinant Mouse Il27ra Protein, Myc/DDK-tagged | +Inquiry |
| IL27RA-1174H | Recombinant Human IL27RA Protein, His (Fc)-Avi-tagged | +Inquiry |
| IL27RA-5203H | Recombinant Human IL27RA Protein, GST-tagged | +Inquiry |
| ◆ Lysates | ||
| IL27RA-2909HCL | Recombinant Human IL27RA cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
- Q&As
- Reviews
Q&As (6)
Ask a questionIn general, Il27ra should be administered by subcutaneous injection. For specific use, follow your doctor's advice and read the drug label carefully.
Il27ra regulates the function of immune cells by binding to its receptor, inhibiting inflammatory response and enhancing antiviral ability.
It is mainly used in clinical treatment of immune-related diseases, such as tumors, autoimmune diseases and so on.
It can be used in conjunction with other medications in certain cases, but be sure to inform your doctor about the medications you are using to avoid the possibility of drug interactions.
The use of Il27ra in children is not yet clear, please follow the guidance of your doctor.
No significant side effects of recombinant Il27ra have been found, but common adverse reactions such as local reactions and anaphylaxis may occur.
Customer Reviews (3)
Write a reviewTechniques such as ELISA or flow cytometry can be used to detect IL-27RA concentrations in body fluids or cells. -
Molecular structure of IL-27RA protein was analyzed by crystallography or NMR, and the binding mode and interaction mechanism with IL-27 were revealed. -
The regulation of IL-27RA on cell signal transduction pathway and changes in cell function were evaluated by cell experiments. -
Ask a Question for All IL27RA Products
Required fields are marked with *
My Review for All IL27RA Products
Required fields are marked with *
Inquiry Basket
