| Description : |
In mice, CD4+ helper T-cells differentiate into type 1 (Th1) cells, which are critical for cell-mediated immunity, predominantly under the influence of IL12. Also, IL4 influences their differentiation into type 2 (Th2) cells, which are critical for most antibody responses. Mice deficient in these cytokines, their receptors, or associated transcription factors have impaired, but are not absent of, Th1 or Th2 immune responses. This gene encodes a protein which is similar to the mouse T-cell cytokine receptor Tccr at the amino acid level, and is predicted to be a glycosylated transmembrane protein. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Fc |
| Form : |
Lyophilized |
| Molecular Mass : |
79 kDa |
| Protein Length : |
636 |
| AA Sequence : |
MRGGRGAPFWLWPLPKLALLPLLWV LFQRTRPQGSAGPLQCYGVGPLGDL NCSWEPLGDLGAPSELHLQSQKYRS NKTQTVAVAAGRSWVAIPREQLTMS DKLLVWGTKAGQPLWPPVFVNLETQ MKPNAPRLGPDVDFSEDDPLEATVH WAPPTWPSHKVLICQFHYRRCQEAA WTLLEPELKTIPLTPVEIQDLELAT GYKVYGRCRMEKEEDLWGEWSPILS FQTPPSAPKDVWVSGNLCGTPGGEE PLLLWKAPGPCVQVSYKVWFWVGGR ELSPEGITCCCSLIPSGAEWARVSA VNATSWEPLTNLSLVCLDSASAPRS VAVSSIAGSTELLVTWQPGPGEPLE HVVDWARDGDPLEKLNWVRLPPGNL SALLPGNFTVGVPYRITVTAVSASG LASASSVWGFREELAPLVGPTLWRL QDAPPGTPAIAWGEVPRHQLRGHLT HYTLCAQSGTSPSVCMNVSGNTQSV TLPDLPWGPCELWVTASTIAGQGPP GPILRLHLPDNTLRWKVLPGILFLW GLFLLGCGLSLATSGRCYHLRHKVL PRWVWEKVPDPANSSSGQPHMEQVP EAQPLGDLPILEVEEMEPPPVMESS QPAQATAPLDSGYEKHFLPTPEELG LLGPPRPQVLA |
| Purity : |
> 98% |
| Applications : |
WB; ELISA; FACS; FC |
| Stability : |
This bioreagent is stable at 4 centigrade (short-term) and -70 centigrade(long-term). After reconstitution, sample may be stored at 4 centigrade for 2-7 days and below -18 centigrade for future use. |
| Storage : |
At -20 centigrade. |
| Concentration : |
1 mg/mL |
| Storage Buffer : |
PBS (pH 7.4-7.5). Sterile-filtered colorless solution. |
| Reconstitution : |
Reconstitute in sterile distilled H2O to no less than 100 μg/mL; dilute reconstituted stock further in other aqueous solutions if needed. Please review COA for lot-specific instructions. Final measurements should be determined by the end-user for optimal performance. |
