• Official Full Name

    interleukin 27 receptor, alpha

  • Background

    In mice, CD4+ helper T-cells differentiate into type 1 (Th1) cells, which are critical for cell-mediated immunity, predominantly under the influence of IL12. Also, IL4 influences their differentiation into type 2 (Th2) cells, which are critical for most antibody responses. Mice deficient in these cytokines, their receptors, or associated transcription factors have impaired, but are not absent of, Th1 or Th2 immune responses. This gene encodes a protein which is similar to the mouse T-cell cytokine receptor Tccr at the amino acid level, and is predicted to be a glycosylated transmembrane protein.
  • Synonyms

    IL27RA; interleukin 27 receptor, alpha; interleukin-27 receptor subunit alpha; CRL1; IL 27R; T cell cytokine receptor type 1; TCCR; WSX 1; WSX1; zcytor1; IL-27RA; IL-27R-alpha; IL-27R subunit alpha; cytokine receptor-like 1; class I cytokine receptor; IL-;
    • Type:
    • Recombinant Proteins
    • Cell & Tissue Lysates
    • Protein Pre-coupled Magnetic Beads
    • Species :
    • Human
    • Mouse
    • Rat
    • Source :
    • CHO
    • E.coli
    • HEK293
    • HEK293T
    • Human Cell
    • Human Cells
    • Mammalian Cell
    • Mammalian cells
    • Wheat Germ
    • Tag :
    • Fc
    • GST
    • His
    • His (Fc)
    • Avi
    • His|T7
    • human IgG1 Fc
    • human|IgG1|Fc
    • Myc
    • DDK
    • Myc|DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human IL27RA-227H Recombinant Human IL27RA protein, Fc-tagged HEK293 human/IgG1/Fc
    Human IL27RA-2909HCL Recombinant Human IL27RA cell lysate Human Cell N/A
    Human IL27RA-018H Recombinant Human IL27RA protein, Fc-tagged HEK293 human IgG1 Fc
    Human IL27RA-5203H Recombinant Human IL27RA Protein, GST-tagged Wheat Germ GST
    Human IL27RA-1928H Recombinant Human IL27RA Protein, MYC/DDK-tagged HEK293 Myc/DDK
    Human IL27RA-783H Active Recombinant Human IL27RA, HIgG1 Fc-tagged CHO Fc
    Human IL27RA-328H Recombinant Human IL27RA Protein, Fc-tagged HEK293 Fc
    Human IL27RA-781H Recombinant Human Interleukin 27 Receptor, Alpha, Fc Chimera E.coli Fc
    Human IL27RA-2622H Recombinant Human IL27RA Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Human Il27RA-782H Active Recombinant Human Il27RA, MIgG2a Fc-tagged CHO Fc
    Human IL27RA-1174H-B Recombinant Human IL27RA Protein Pre-coupled Magnetic Beads HEK293
    Human IL27RA-5788H Recombinant Human IL27RA protein, His & T7-tagged E.coli His/T7
    Human IL27RA-151H Recombinant Human IL27RA Protein, DYKDDDDK-tagged Human Cells DYKDDDDK
    Human Il27RA-1629H Recombinant Human Il27RA protein, Fc-tagged HEK293 Fc
    Human IL27RA-1174H Recombinant Human IL27RA Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
    Mouse Il27ra-1013M Active Recombinant Mouse Il27ra Protein, Fc Chimera Mammalian cells Fc
    Mouse Il27ra-660M Active Recombinant Mouse Interleukin 27 Receptor, Alpha, Fc-tagged Mammalian cells Fc
    Mouse Il27ra-5789M Recombinant Mouse Il27ra protein, His & T7-tagged E.coli His/T7
    Mouse Il27ra-3519M Recombinant Mouse Il27ra Protein, Myc/DDK-tagged HEK293T Myc/DDK
    Mouse IL27RA-8161M Recombinant Mouse IL27RA Protein Mammalian Cell His
    Mouse Il27ra-72M Recombinant Mouse Il27ra Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
    Mouse Il27ra-72M-B Recombinant Mouse Il27ra Protein Pre-coupled Magnetic Beads HEK293
    Rat Il27ra-5790R Recombinant Rat Il27ra protein, His & T7-tagged E.coli His/T7
    • Involved Pathway
    • Protein Function
    • Interacting Protein
    • IL27RA Related Gene Family

    IL27RA involved in several pathways and played different roles in them. We selected most pathways IL27RA participated on our site, such as Jak-STAT signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with IL27RA were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Jak-STAT signaling pathwayPIK3R5;PIK3R3B;CRFB16;OSMR;PTPN2;IL12BA;IFNB1;IL20RA;PIK3R3

    IL27RA has several biochemical functions, for example, interleukin-27 receptor activity, transmembrane signaling receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by IL27RA itself. We selected most functions IL27RA had, and list some proteins which have the same functions with IL27RA. You can find most of the proteins on our site.

    Function Related Protein
    interleukin-27 receptor activityIL6ST;IL27RA
    transmembrane signaling receptor activityLGR4;ADCYAP1R1A;TLR1;OR2A4;TLR18;IL27RA;OR4C13;IGSF6;FZD1

    IL27RA has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with IL27RA here. Most of them are supplied by our site. Hope this information will be useful for your research of IL27RA.

    • Q&As
    • Reviews

    Q&As (6)

    Ask a question
    What is the use of Il27ra? 07/02/2022

    In general, Il27ra should be administered by subcutaneous injection. For specific use, follow your doctor's advice and read the drug label carefully.

    What is the action mechanism of Il27ra? 02/10/2022

    Il27ra regulates the function of immune cells by binding to its receptor, inhibiting inflammatory response and enhancing antiviral ability.

    Does the clinical applications of Il27ra? 09/08/2020

    It is mainly used in clinical treatment of immune-related diseases, such as tumors, autoimmune diseases and so on.

    Can Il27ra be used with other drugs? 10/29/2019

    It can be used in conjunction with other medications in certain cases, but be sure to inform your doctor about the medications you are using to avoid the possibility of drug interactions.

    Can Il27ra be used in children? 09/27/2019

    The use of Il27ra in children is not yet clear, please follow the guidance of your doctor.

    What are the side effects of Il27ra? 08/19/2019

    No significant side effects of recombinant Il27ra have been found, but common adverse reactions such as local reactions and anaphylaxis may occur.

    Customer Reviews (3)

    Write a review

      Techniques such as ELISA or flow cytometry can be used to detect IL-27RA concentrations in body fluids or cells. -


        Molecular structure of IL-27RA protein was analyzed by crystallography or NMR, and the binding mode and interaction mechanism with IL-27 were revealed. -


          The regulation of IL-27RA on cell signal transduction pathway and changes in cell function were evaluated by cell experiments. -

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