• Official Full Name

    interleukin 27 receptor, alpha

  • Overview

    In mice, CD4+ helper T-cells differentiate into type 1 (Th1) cells, which are critical for cell-mediated immunity, predominantly under the influence of IL12. Also, IL4 influences their differentiation into type 2 (Th2) cells, which are critical for most antibody responses. Mice deficient in these cytokines, their receptors, or associated transcription factors have impaired, but are not absent of, Th1 or Th2 immune responses. This gene encodes a protein which is similar to the mouse T-cell cytokine receptor Tccr at the amino acid level, and is predicted to be a glycosylated transmembrane protein.
  • Synonyms

    IL27RA; interleukin 27 receptor, alpha; interleukin-27 receptor subunit alpha; CRL1; IL 27R; T cell cytokine receptor type 1; TCCR; WSX 1; WSX1; zcytor1; IL-27RA; IL-27R-alpha; IL-27R subunit alpha; cytokine receptor-like 1; class I cytokine receptor; IL-;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Mus musculus (Mouse)
  • Rat
  • CHO
  • E.coli
  • E.coli expression system
  • HEK293
  • HEK293T
  • Human Cell
  • Human Cells
  • Mammalian Cell
  • Mammalian cells
  • Wheat Germ
  • C
  • hFc
  • His
  • Fc
  • Flag
  • GST
  • His (Fc)
  • Avi
  • His|T7
  • human IgG1 Fc
  • human|IgG1|Fc
  • Myc
  • DDK
  • Myc|DDK
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human IL27RA-783H Active Recombinant Human IL27RA, HIgG1 Fc-tagged CHO Fc
Human Il27RA-782H Active Recombinant Human Il27RA, MIgG2a Fc-tagged CHO Fc
Human IL27RA-228H Active Recombinant Human IL27RA protein, C-His-tagged, 33-514 aa HEK293 C-His Gln 33 - Arg 514
Human Il27RA-1629H Active Recombinant Human Il27RA protein(Met1-Arg514), hFc-tagged HEK293 C-hFc Met1-Arg514
Human IL27RA-227H Recombinant Human IL27RA protein, Fc-tagged HEK293 human/IgG1/Fc Gln33-Arg514
Human IL27RA-781H Recombinant Human Interleukin 27 Receptor, Alpha, Fc Chimera E.coli Fc
Human IL27RA-5788H Recombinant Human IL27RA protein, His & T7-tagged E.coli His/T7 Glu123~Pro343 (Accession # Q6UWB1)
Human IL27RA-2909HCL Recombinant Human IL27RA cell lysate Human Cell N/A
Human IL27RA-018H Recombinant Human IL27RA protein, Fc-tagged HEK293 human IgG1 Fc Gln33-Arg514
Human IL27RA-3305H Recombinant Human IL27RA Protein (Glu123-Pro343), N-His tagged E.coli N-His Glu123-Pro343
Human IL27RA-1928H Recombinant Human IL27RA Protein, MYC/DDK-tagged HEK293 Myc/DDK
Human IL27RA-5203H Recombinant Human IL27RA Protein, GST-tagged Wheat Germ GST
Human IL27RA-328H Recombinant Human IL27RA Protein, Fc-tagged HEK293 Fc 636
Human IL27RA-2622H Recombinant Human IL27RA Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human IL27RA-1174H-B Recombinant Human IL27RA Protein Pre-coupled Magnetic Beads HEK293
Human IL27RA-151H Recombinant Human IL27RA Protein, DYKDDDDK-tagged Human Cells DYKDDDDK
Human IL27RA-876HFL Recombinant Full Length Human IL27RA Protein, C-Flag-tagged Mammalian cells Flag
Human IL27RA-1174H Recombinant Human IL27RA Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Il27ra-1013M Active Recombinant Mouse Il27ra Protein, Fc Chimera Mammalian cells Fc
Mouse Il27ra-660M Active Recombinant Mouse Interleukin 27 Receptor, Alpha, Fc-tagged Mammalian cells Fc
Mouse IL27RA-8161M Recombinant Mouse IL27RA Protein Mammalian Cell His
Mouse Il27ra-5789M Recombinant Mouse Il27ra protein, His & T7-tagged E.coli His/T7 Leu117~Ala350 (Accession # O70394)
Mouse Il27ra-3519M Recombinant Mouse Il27ra Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse Il27ra-72M Recombinant Mouse Il27ra Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Il27ra-72M-B Recombinant Mouse Il27ra Protein Pre-coupled Magnetic Beads HEK293
Rat Il27ra-5790R Recombinant Rat Il27ra protein, His & T7-tagged E.coli His/T7 Thr93~Gln273 (Accession # D4A6K5)
Mus musculus (Mouse) RFL13570MF Recombinant Full Length Mouse Interleukin-27 Receptor Subunit Alpha(Il27Ra) Protein, His-Tagged E.coli expression system His Full Length of Mature Protein (25-623)
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • Other Resource

IL27RA involved in several pathways and played different roles in them. We selected most pathways IL27RA participated on our site, such as Jak-STAT signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with IL27RA were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Jak-STAT signaling pathwayIL23;IFNL3;IL12A;Il23a;SOCS1;STAT6;MPL;IL7;PRL

IL27RA has several biochemical functions, for example, interleukin-27 receptor activity, transmembrane signaling receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by IL27RA itself. We selected most functions IL27RA had, and list some proteins which have the same functions with IL27RA. You can find most of the proteins on our site.

Function Related Protein
interleukin-27 receptor activityIL6ST;IL27RA
transmembrane signaling receptor activityPTH1RB;TLR5;FZD3A;FZD7B;OR2A4;TLR9;CALCRLA;EBP;SPN

IL27RA has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with IL27RA here. Most of them are supplied by our site. Hope this information will be useful for your research of IL27RA.

Gene Family


Research Area

  • Q&As
  • Reviews

Q&As (6)

Ask a question
What is the use of Il27ra? 07/02/2022

In general, Il27ra should be administered by subcutaneous injection. For specific use, follow your doctor's advice and read the drug label carefully.

What is the action mechanism of Il27ra? 02/10/2022

Il27ra regulates the function of immune cells by binding to its receptor, inhibiting inflammatory response and enhancing antiviral ability.

Does the clinical applications of Il27ra? 09/08/2020

It is mainly used in clinical treatment of immune-related diseases, such as tumors, autoimmune diseases and so on.

Can Il27ra be used with other drugs? 10/29/2019

It can be used in conjunction with other medications in certain cases, but be sure to inform your doctor about the medications you are using to avoid the possibility of drug interactions.

Can Il27ra be used in children? 09/27/2019

The use of Il27ra in children is not yet clear, please follow the guidance of your doctor.

What are the side effects of Il27ra? 08/19/2019

No significant side effects of recombinant Il27ra have been found, but common adverse reactions such as local reactions and anaphylaxis may occur.

Customer Reviews (3)

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    Good stability, stable structure, not easy to deteriorate.


      The preparation process is very convenient and suitable for novice operators.


        This method is highly sensitive and can detect small amounts of protein.

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