Recombinant Human IL2RB protein, His-Avi-tagged, Biotinylated

• Cat.No.: IL2RB-869HB
• Product Overview: Biotinylated Recombinant Human CD122 Protein is expressed from mammalian with His Tag and Avi Tag at the C-terminal. It contains Ala 27-Asp 239.

Specification

• Description: IL-2 R beta is a member of the cytokine receptor superfamily. Human IL-2 R beta cDNA encodes a 551 amino acid residue precursor Type I membrane protein with a 26 residue signal peptide, a 214 residue extracellular region, a 25 residue transmembrane region and a 286 residue cytoplasmic domain. Functional IL-2 receptors can exist in two affinity states on cell surfaces, the high affinity complex consisting of heterotrimers of the alpha, beta, and gamma chains, and the intermediate affinity complex comprising heterodimers of the beta and gamma chains.
• Source: HEK293
• Species: Human
• Tag: His-Avi
• Form: Supplied as 0.22um filtered solution in PBS (pH 7.4).
• Molecular Mass: The protein has a predicted MW of 27.5 KDa. Due to glycosylation, the protein migrates to 40-50KDa based on Bis-Tris PAGE result.
• Protein length: Ala 27-Asp 239
• Endotoxin: Less than 0.05 EU per ug by the LAL method.
• Purity: > 95% as determined by Bis-Tris PAGE; > 95% as determined by HPLC
• Storage: The product should be stored at -70°C. Please do not repeated freeze-thaw cycles.

Gene Information

• Gene Name: IL2RB
• Official Symbol: IL2RB
• Synonyms: CD122 antigen; CD122; high affinity IL-2 receptor beta subunit; High affinity IL-2 receptor subunit beta; IL-15 R beta; IL-2 R beta; IL-2 receptor subunit beta; IL2R beta; IL-2R subunit beta; IL2RB; IL-2Rb; interleukin 15 receptor, beta; interleukin 2 receptor, beta; interleukin-2 receptor subunit beta; P70-75; p75
• Gene ID: 3560
• mRNA Refseq: NM_000878.5
• Protein Refseq: NP_000869.1
• MIM: 146710
• UniProt ID: P14784