Recombinant Human IL33 Protein, N-Avi tagged, Biotinylated

• Cat.No.: IL33-45H
• Product Overview: Biotinylated recombinant Human IL-33 is produced by E.coli. The target gene encoding S111-T270 is expressed with a N-AVI tag.

Specification

• Description: Interleukin 33 (IL-33) is a cytokine that belongs to the IL-1 superfamily. IL-33 is expressed at high level in high endothelial venules found in tonsils, Peyer patches and mesenteric lymph nodes. As a type 2 cytokines, IL-33 plays a central role in helminthic infection and allergic disorders by amplifying immune responses during tissue injury. Studies also suggested that IL-33 might act as an intracellular nuclear factor besides the function of cytokine.
• Source: E. coli
• Species: Human
• Tag: N-Avi
• Protein Length: S111-T270
• Storage Buffer: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.2.
• Shipping: Ambient

Gene Information

• Gene Name: IL33 interleukin 33 [ Homo sapiens (human) ]
• Official Symbol: IL33
• Synonyms: Interleukin-33; IL-33; Interleukin-1 Family Member 11; IL-1F11; Nuclear Factor From HighEndothelial Venules; NF-HEV; IL33; C9orf26; IL1F11; NFHEV
• Gene ID: 90865
• mRNA Refseq: NM_001199640
• Protein Refseq: NP_001186569
• MIM: 608678
• UniProt ID: O95760

Reviews

10/16/2021

Good solubility and is easy to operate and purify.

05/03/2021

Effectively mimics the function of the target protein in vitro.

03/18/2020

IL33 has a wide range of applications in the field of scientific research and is suitable for a variety of experimental design and research purposes.

Q&As

Which immune cells can recombinant IL33 be used to detect?

It can be used to detect immune cells such as macrophages and dendritic cells.

In what research fields can recombinant IL33 be applied?

This protein applied in immunology, drug research, life science and other fields.

What is the action mechanism of IL33?

Regulates the activity of immune cells by binding to receptors to stimulate the production of inflammatory factors such as interferon and TNF-α.

Besides treating asthma and hay fever, what other diseases can be treated with IL33?

IL33 can also be used to treat a variety of inflammatory diseases, such as inflammatory bowel disease, psoriasis and so on.

How to prepare IL33?

The preparation of IL33 requires first cloning the IL33 gene into the expression vector, and then the expression vector is expressed and purified in the cell culture medium.

How long does it take to treat asthma with IL33?

Treating asthma with recombinant IL33 takes several weeks to several months to be effective, depending on the severity of the condition and the individual patient.