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Recombinant Human IL6ST protein, DDDDK-tagged

Cat.No. : IL6ST-272H
Product Overview : Recombinant Human IL6ST protein(NP_002175.2) (Met1-Ile618) was expressed with five amino acids (DDDDK) at the C-terminus.
  • Specification
  • Gene Information
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Source : HEK293
Species : Human
Tag : DDDDK
Form : Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Molecular Mass : The recombinant human IL6RB consists of 602 amino acids and predicts a molecular mass of 68.4 KDa. It migrates as an approximately 94.9 KDa band in SDS-PAGE under reducing conditions due to glycosylation.
Protein length : Met1-Ile618
Endotoxin : < 1.0 EU per μg protein as determined by the LAL method.
Purity : > 90 % as determined by SDS-PAGE.
Storage : Samples are stable for up to twelve months from date of receipt at -20ºC to -80ºC
Store it under sterile conditions at -20ºC to -80ºC. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Gene Name : IL6ST interleukin 6 signal transducer (gp130, oncostatin M receptor) [ Homo sapiens ]
Official Symbol : IL6ST
Synonyms : IL6ST; interleukin 6 signal transducer (gp130, oncostatin M receptor); interleukin-6 receptor subunit beta; CD130; GP130; CD130 antigen; IL-6R subunit beta; membrane glycoprotein 130; IL-6 receptor subunit beta; membrane glycoprotein gp130; interleukin receptor beta chain; oncostatin-M receptor subunit alpha; gp130 of the rheumatoid arthritis antigenic peptide-bearing soluble form; CDW130; IL-6RB; DKFZp564F053;
Gene ID : 3572
mRNA Refseq : NM_001190981.1
Protein Refseq : NP_001177910.1
MIM : 600694
UniProt ID : P40189

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (6)

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How to detect IL6ST activity? 04/26/2022

The activity of IL6ST is usually detected by cell differentiation and proliferation assay.

In what diseases does IL6ST have applications? 04/20/2021

IL6ST may be used in the future to treat pulmonary fibrosis, chronic pulmonary obstruction, rheumatoid arthritis, and other chronic kidney diseases.

Are there any effects of IL6ST on cell differentiation? 04/15/2021

IL6ST is involved in various inflammatory responses and cell differentiation processes.

What are the physical and chemical properties of IL6ST? 02/03/2021

The physical and chemical properties of IL6ST include molecular weight, voltammetry potential, structure and stability.

Why research IL6ST? 02/09/2019

The study of IL6ST helps us to better understand the disease mechanism involved in IL6ST, and provides new ideas and means for disease treatment.

What is the preparation method of IL6ST? 01/27/2019

The IL6ST is usually prepared by transforming E. coli into an expression vector and making it express the IL6ST protein.

Customer Reviews (3)

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Reviews
02/28/2022

    IL6ST proteins can be functionally enhanced or altered by protein modification techniques.

    08/04/2020

      As an immunotherapy drug, it has good effect and high safety.

      09/06/2019

        Has a good inhibitory effect on cell proliferation and survival.

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