Recombinant Human ILKAP Protein, GST-tagged
Cat.No. : | ILKAP-5156H |
Product Overview : | Human ILKAP full-length ORF ( AAH06576, 1 a.a. - 392 a.a.) recombinant protein with GST-tag at N-terminal. |
- Specification
- Gene Information
- Related Products
Description : | The protein encoded by this gene is a protein serine/threonine phosphatase of the PP2C family. This protein can interact with integrin-linked kinase (ILK/ILK1), a regulator of integrin mediated signaling, and regulate the kinase activity of ILK. Through the interaction with ILK, this protein may selectively affect the signaling process of ILK-mediated glycogen synthase kinase 3 beta (GSK3beta), and thus participate in Wnt signaling pathway. [provided by RefSeq |
Source : | Wheat Germ |
Species : | Human |
Tag : | GST |
Molecular Mass : | 68.86 kDa |
AA Sequence : | MDLFGDLPEPERSPRPAAGKEAQKG PLLFDDLPPASSTDSGSGGPLLFDD LPPASSGDSGSLATSISQMVKTEGK GAKRKTSEEEKNGSEELVEKKVCKA SSVIFGLKGYVAERKGEREEMQDAH VILNDITEECRPPSSLITRVSYFAV FDGHGGIRASKFAAQNLHQNLIRKF PKGDVISVEKTVKRCLLDTFKHTDE EFLKQASSQKPAWKDGSTATCVLAV DNILYIANLGDSRAILCRYNEESQK HAALSLSKEHNPTQYEERMRIQKAG GNVRDGRVLGVLEVSRSIGDGQYKR CGVTSVPDIRRCQLTPNDRFILLAC DGLFKVFTPEEAVNFILSCLEDEKI QTREGKSAADARYEAACNRLANKAV QRGSADNVTVMVVRIGH |
Applications : | Enzyme-linked Immunoabsorbent Assay Western Blot (Recombinant protein) Antibody Production Protein Array |
Notes : | Best use within three months from the date of receipt of this protein. |
Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Gene Name : | ILKAP integrin-linked kinase-associated serine/threonine phosphatase [ Homo sapiens ] |
Official Symbol : | ILKAP |
Synonyms : | ILKAP; integrin-linked kinase-associated serine/threonine phosphatase; integrin linked kinase associated serine/threonine phosphatase 2C; integrin-linked kinase-associated serine/threonine phosphatase 2C; DKFZP434J2031; FLJ10181; protein phosphatase 2c, delta isozyme; integrin-linked kinase associated phosphatase; ILKAP2; ILKAP3; PP2C-DELTA; MGC4846; DKFZp434J2031; |
Gene ID : | 80895 |
mRNA Refseq : | NM_030768 |
Protein Refseq : | NP_110395 |
UniProt ID : | Q9H0C8 |
Products Types
◆ Recombinant Protein | ||
ILKAP-2709R | Recombinant Rat ILKAP Protein, His (Fc)-Avi-tagged | +Inquiry |
ILKAP-2174H | Recombinant Human ILKAP Protein, MYC/DDK-tagged | +Inquiry |
ILKAP-4526M | Recombinant Mouse ILKAP Protein, His (Fc)-Avi-tagged | +Inquiry |
Ilkap-3526M | Recombinant Mouse Ilkap Protein, Myc/DDK-tagged | +Inquiry |
ILKAP-14217H | Recombinant Human ILKAP, His-tagged | +Inquiry |
◆ Lysates | ||
ILKAP-1855HCL | Recombinant Human ILKAP cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
- Q&As
- Reviews
Q&As (6)
Ask a questionILKAP is a serine/threonine protein phosphatase that is intracellular localized in the cytoplasm and cytoskeleton and interacts with Integrin-linked kinase (ILK).
It has been shown that ILKAP may interact with NF-κB and JAK/STAT signaling pathways, but further studies are needed to clarify the specific role and mechanism.
ILKAP may be involved in the process of immune regulation and affect the activity and response of immune cells, but the specific role needs to be further studied.
Some studies have shown that ILKAP expression level decreased in some tumors may be associated with poor prognosis of tumour, but the specific mechanism still need more study.
Several studies have suggested that ILKAP may play a role in apoptosis, thereby affecting cell survival and proliferation.
The interaction between ILKAP and ILK, and may be involved in cell adhesion, movement and biological processes such as signal transmission.
Customer Reviews (3)
Write a reviewNo doping impurities, the experimental results are very good, will recommend to other students.
The sensitivity is very high, the experimental results are very good, and the unnecessary trouble is reduced.
Not easy to inactivate, tried a variety of experimental conditions, still active.
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