Creative BioMart to Present at
                        BIO-Europe Spring Creative BioMart to Present at AACR Annual Meeting|Apr. 5-10, 2024|Booth #2953

Recombinant Human ILKAP Protein, GST-tagged

Cat.No. : ILKAP-5156H
Product Overview : Human ILKAP full-length ORF ( AAH06576, 1 a.a. - 392 a.a.) recombinant protein with GST-tag at N-terminal.
  • Specification
  • Gene Information
  • Related Products
Description : The protein encoded by this gene is a protein serine/threonine phosphatase of the PP2C family. This protein can interact with integrin-linked kinase (ILK/ILK1), a regulator of integrin mediated signaling, and regulate the kinase activity of ILK. Through the interaction with ILK, this protein may selectively affect the signaling process of ILK-mediated glycogen synthase kinase 3 beta (GSK3beta), and thus participate in Wnt signaling pathway. [provided by RefSeq
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 68.86 kDa
AA Sequence : MDLFGDLPEPERSPRPAAGKEAQKG PLLFDDLPPASSTDSGSGGPLLFDD LPPASSGDSGSLATSISQMVKTEGK GAKRKTSEEEKNGSEELVEKKVCKA SSVIFGLKGYVAERKGEREEMQDAH VILNDITEECRPPSSLITRVSYFAV FDGHGGIRASKFAAQNLHQNLIRKF PKGDVISVEKTVKRCLLDTFKHTDE EFLKQASSQKPAWKDGSTATCVLAV DNILYIANLGDSRAILCRYNEESQK HAALSLSKEHNPTQYEERMRIQKAG GNVRDGRVLGVLEVSRSIGDGQYKR CGVTSVPDIRRCQLTPNDRFILLAC DGLFKVFTPEEAVNFILSCLEDEKI QTREGKSAADARYEAACNRLANKAV QRGSADNVTVMVVRIGH
Applications : Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Gene Name : ILKAP integrin-linked kinase-associated serine/threonine phosphatase [ Homo sapiens ]
Official Symbol : ILKAP
Synonyms : ILKAP; integrin-linked kinase-associated serine/threonine phosphatase; integrin linked kinase associated serine/threonine phosphatase 2C; integrin-linked kinase-associated serine/threonine phosphatase 2C; DKFZP434J2031; FLJ10181; protein phosphatase 2c, delta isozyme; integrin-linked kinase associated phosphatase; ILKAP2; ILKAP3; PP2C-DELTA; MGC4846; DKFZp434J2031;
Gene ID : 80895
mRNA Refseq : NM_030768
Protein Refseq : NP_110395
UniProt ID : Q9H0C8

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

Inquiry

  • Q&As
  • Reviews

Q&As (6)

Ask a question
What is the function of ILKAP? What is the localization inside the cell? 10/02/2019

ILKAP is a serine/threonine protein phosphatase that is intracellular localized in the cytoplasm and cytoskeleton and interacts with Integrin-linked kinase (ILK).

Which signaling pathways are involved in ILKAP? 08/19/2019

It has been shown that ILKAP may interact with NF-κB and JAK/STAT signaling pathways, but further studies are needed to clarify the specific role and mechanism.

How does ILKAP play a role in immune regulation? 08/06/2019

ILKAP may be involved in the process of immune regulation and affect the activity and response of immune cells, but the specific role needs to be further studied.

Is ILKAP expression level correlated with tumor prognosis? 05/08/2019

Some studies have shown that ILKAP expression level decreased in some tumors may be associated with poor prognosis of tumour, but the specific mechanism still need more study.

What is the role of ILKAP in apoptosis? 04/19/2019

Several studies have suggested that ILKAP may play a role in apoptosis, thereby affecting cell survival and proliferation.

How do ILKAP and ILK interact with each other? 03/17/2019

The interaction between ILKAP and ILK, and may be involved in cell adhesion, movement and biological processes such as signal transmission.

Customer Reviews (3)

Write a review
Reviews
11/04/2022

    No doping impurities, the experimental results are very good, will recommend to other students.

    05/26/2022

      The sensitivity is very high, the experimental results are very good, and the unnecessary trouble is reduced.

      09/30/2021

        Not easy to inactivate, tried a variety of experimental conditions, still active.

        Ask a Question for All ILKAP Products

        Required fields are marked with *

        My Review for All ILKAP Products

        Required fields are marked with *

        0

        Inquiry Basket

        cartIcon
        logo

        FOLLOW US

        Terms and Conditions        Privacy Policy

        Copyright © 2024 Creative BioMart. All Rights Reserved.

        Contact Us

        • /

        Stay Updated on the Latest Bioscience Trends