Recombinant Human IMMP1L Protein, GST-tagged

• Cat.No.: IMMP1L-5153H
• Product Overview: Human IMMP1L full-length ORF ( NP_659418.1, 1 a.a. - 166 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: The mitochondrial inner membrane peptidase (IMP) complex generates mature, active proteins in the mitochondrial intermembrane space by proteolytically removing the mitochondrial targeting presequence of nuclear-encoded proteins. IMP1 and IMP2 (IMMP2L; MIM 605977) are the catalytic subunits of the IMP complex (Burri et al., 2005 [PubMed 15814844]).[supplied by OMIM
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 44.9 kDa
• AA Sequence: MLRGVLGKTFRLVGYTIQYGCIAHC AFEYVGGVVMCSGPSMEPTIQNSDI VFAENLSRHFYGIQRGDIVIAKSPS DPKSNICKRVIGLEGDKILTTSPSD FFKSHSYVPMGHVWLEGDNLQNSTD SRCYGPIPYGLIRGRIFFKIWPLSD FGFLRASPNGHRFSDD
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: IMMP1L IMP1 inner mitochondrial membrane peptidase-like (S. cerevisiae) [ Homo sapiens ]
• Official Symbol: IMMP1L
• Synonyms: IMP1; IMP1-LIKE; IMMP1L; IMP1 inner mitochondrial membrane peptidase-like (S. cerevisiae)
• Gene ID: 196294
• mRNA Refseq: NM_144981
• Protein Refseq: NP_659418
• MIM: 612323
• UniProt ID: Q96LU5

Reviews

07/16/2020

High expression level, good stability, suitable for high precision experiments.

01/13/2020

Strong antibacterial activity, not easy to be contaminated.

07/04/2019

It's good in ELISA. It's good for an immunoassay.

Q&As

What signaling pathways does IMMP1L interact with?

This protein interacts with mitochondrial membrane potential, ATP production, cell death, and mitochondrial DNA maintenance signaling pathways.

What diseases is IMMP1L involved in?

The research of IMMP1L is related to neurodegenerative diseases, cardiomyopathy and mitochondrial diseases because of its important role in cellular energy metabolism.

In which tissues or organs is IMMP1L highly expressed?

IMMP1L in multiple tissues and organs have certain expression, especially in high expressed in the heart, muscles and nervous system.

What is the function of IMMP1L in cellular processes?

It participate in peptide enzyme complexes in mitochondrial membrane assembly, mature and regulation plays an important role for protein.

How does IMMP1L regulate apoptosis?

It may be involved in the regulation of apoptosis by regulating mitochondrial membrane potential, mitochondrial protein stability and the release of cell death-related factors.

Does IMMP1L interact directly with other proteins?

IMMP1L interacts with several proteins, such as IMM22 and GFER, and these interactions may play important functions in cells.