Recombinant Human IMPDH2 Protein, Myc/DDK-tagged, C13 and N15-labeled
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| Cat.No. : | IMPDH2-4161H |
| Product Overview : | IMPDH2 MS Standard C13 and N15-labeled recombinant protein (NP_000875) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells. |
| Description : | This gene encodes the rate-limiting enzyme in the de novo guanine nucleotide biosynthesis. It is thus involved in maintaining cellular guanine deoxy- and ribonucleotide pools needed for DNA and RNA synthesis. The encoded protein catalyzes the NAD-dependent oxidation of inosine-5'-monophosphate into xanthine-5'-monophosphate, which is then converted into guanosine-5'-monophosphate. This gene is up-regulated in some neoplasms, suggesting it may play a role in malignant transformation. |
| Source : | HEK293 |
| Species : | Human |
| Tag : | Myc/DDK |
| Molecular Mass : | 55.8 kDa |
| AA Sequence : | MADYLISGGT SYVPDDGLTA QQLFNCGDGL TYNDFLILPG YIDFTADQVD LTSALTKKIT LKTPLVSSPM DTVTEAGMAI AMALTGGIGF IHHNCTPEFQ ANEVRKVKKY EQGFITDPVV LSPKDRVRDV FEAKARHGFC GIPITDTGRM GSRLVGIISS RDIDFLKEEE HDCFLEEIMT KREDLVVAPA GITLKEANEI LQRSKKGKLP IVNEDDELVA IIARTDLKKN RDYPLASKDA KKQLLCGAAI GTHEDDKYRL DLLAQAGVDV VVLDSSQGNS IFQINMIKYI KDKYPNLQVI GGNVVTAAQA KNLIDAGVDA LRVGMGSGSI CITQEVLACG RPQATAVYKV SEYARRFGVP VIADGGIQNV GHIAKALALG ASTVMMGSLL AATTEAPGEY FFSDGIRLKK YRGMGSLDAM DKHLSSQNRY FSEADKIKVA QGVSGAVQDK GSIHKFVPYL IAGIQHSCQD IGAKSLTQVR AMMYSGELKF EKRTSSAQVE GGVHSLHSYE KRLFTRTRPL EQKLISEEDL AANDILDYKD DDDKV |
| Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : | Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : | Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : | 50 μg/mL as determined by BCA |
| Storage Buffer : | 100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
| SDS-PAGE : |
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| Gene Name : | IMPDH2 inosine monophosphate dehydrogenase 2 [ Homo sapiens (human) ] |
| Official Symbol : | IMPDH2 |
| Synonyms : | IMPDH2; IMP (inosine 5-monophosphate) dehydrogenase 2; inosine-5-monophosphate dehydrogenase 2; IMPD 2; IMPDH 2; IMP oxireductase 2; inosine 5 phosphate dehydrogenase 2; IMP (inosine monophosphate) dehydrogenase 2; inosine monophosphate dehydrogenase type II; IMPD2; IMPDH-II; |
| Gene ID : | 3615 |
| mRNA Refseq : | NM_000884 |
| Protein Refseq : | NP_000875 |
| MIM : | 146691 |
| UniProt ID : | P12268 |
◆ Recombinant Protein
| IMPDH2-5138H | Recombinant Human IMPDH2 Protein, GST-tagged | +Inquiry |
| IMPDH2-299H | Recombinant Human IMPDH2 Protein, His-tagged | +Inquiry |
| Impdh2-3532M | Recombinant Mouse Impdh2 Protein, Myc/DDK-tagged | +Inquiry |
| IMPDH2-01H | Recombinant Human IMPDH2 Protein, His-tagged | +Inquiry |
| IMPDH2-1276H | Recombinant Human IMPDH2, MYC/DDK-tagged | +Inquiry |
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◆ Lysates
| IMPDH2-5210HCL | Recombinant Human IMPDH2 293 Cell Lysate | +Inquiry |
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