Recombinant Human ING5 Protein, GST-tagged

• Cat.No.: ING5-5124H
• Product Overview: Human ING5 full-length ORF ( NP_115705.2, 1 a.a. - 240 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: The protein encoded by this gene is similar to ING1, a tumor suppressor protein that can interact with TP53, inhibit cell growth, and induce apoptosis. This protein contains a PHD-finger, which is a common motif in proteins involved in chromatin remodeling. This protein can bind TP53 and EP300/p300, a component of the histone acetyl transferase complex, suggesting its involvement in TP53-dependent regulatory pathway. [provided by RefSeq
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 54.2 kDa
• AA Sequence: MATAMYLEHYLDSIENLPCELQRNF QLMRELDQRTEDKKAEIDILAAEYI STVKTLSPDQRVERLQKIQNAYSKC KEYSDDKVQLAMQTYEMVDKHIRRL DADLARFEADLKDKMEGSDFESSGG RGLKKGRGQKEKRGSRGRGRRTSEE DTPKKKKHKGGSEFTDTILSVHPSD VLDMPVDPNEPTYCLCHQVSYGEMI GCDNPDCPIEWFHFACVDLTTKPKG KWFCPRCVQEKRKKK
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: ING5 inhibitor of growth family, member 5 [ Homo sapiens ]
• Official Symbol: ING5
• Synonyms: ING5; inhibitor of growth family, member 5; inhibitor of growth protein 5; FLJ23842; p28ING5
• Gene ID: 84289
• mRNA Refseq: NM_032329
• Protein Refseq: NP_115705
• MIM: 608525
• UniProt ID: Q8WYH8