Recombinant Human INS-IGF2 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: INS-IGF2-3839H
• Product Overview: INS MS Standard C13 and N15-labeled recombinant protein (NP_001035835) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Species: Human
• Source: HEK293
• Tag: DDK&Myc
• Description: This locus includes two alternatively spliced read-through transcript variants which align to the INS gene in the 5' region and to the IGF2 gene in the 3' region. One transcript is predicted to encode a protein which shares the N-terminus with the INS protein but has a distinct and longer C-terminus, whereas the other transcript is a candidate for nonsense-mediated decay (NMD). The transcripts are imprinted and are paternally expressed in the limb and eye.
• Molecular Mass: 21.4 kDa
• AA Sequence: MALWMRLLPLLALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQASALSLSSSTSTWPEGLDATARAPPALVVTANIGQAGGSSSRQFRQRALGTSDSPVLFIHCPGAAGTAQGLEYRGRRVTTELVWEEVDSSPQPQGSESLPAQPPAQPAPQPEPQQAREPSPEVSCCGLWPRRPQRSQNTRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: INS-IGF2 INS-IGF2 readthrough [ Homo sapiens (human) ]
• Official Symbol: INS-IGF2
• Synonyms: INS-IGF2; INS-IGF2 readthrough; INSIGF; insulin, isoform 2; INS-IGF2 readthrough transcript protein; insulin; insulin- insulin-like growth factor 2 read-through product
• Gene ID: 723961
• mRNA Refseq: NM_001042376
• Protein Refseq: NP_001035835
• UniProt ID: F8WCM5