Recombinant Human INSC Protein, GST-tagged
Cat.No. : | INSC-5099H |
Product Overview : | Human INSC full-length ORF ( AAI56333.1, 1 a.a. - 579 a.a.) recombinant protein with GST-tag at N-terminal. |
- Specification
- Gene Information
- Related Products
Description : | In Drosophila, neuroblasts divide asymmetrically into another neuroblast at the apical side and a smaller ganglion mother cell on the basal side. Cell polarization is precisely regulated by 2 apically localized multiprotein signaling complexes that are tethered by Inscuteable, which regulates their apical localization (Izaki et al., 2006 [PubMed 16458856]).[supplied by OMIM |
Source : | Wheat Germ |
Species : | Human |
Tag : | GST |
Molecular Mass : | 63.7 kDa |
AA Sequence : | MRRPPGNGEAASEGPGGWGLWGVQE SRRLCCAGHDRCKQALLQIGINMMA LPGGRHLDSVTLPGQRLHLMQVDSV QRWMEDLKLMTECECMCVLQAKPIS LEEDAQGDLILAGGPGPGDPLQLLL KRGWVISTELRRIGQKLAQDRWARV HSMSVRLTCHARSMVSEYSAVSRNS LKEMGEIEKLLMEKCSELSAVTERC LQVENEHVLKSMKACVSETLSMLGQ HFGQLLELALTREVQALVRKIDASD NIYTTESTTGNLFSLTQEGAPLCRI IAKEGGVVALFKVCRQDSFRCLYPQ ALRTLASICCVEEGVHQLEKVDGVL CLADILTDNSHSEATRAEAAAVVAQ VTSPHLPVTQHLSSFLESMEEIVTA LVKLCQEASSGEVFLLASAALANIT FFDTMACEMLLQLNAIRVLLEACSD KQRVDTPYTRDQIVTILANMSVLEQ CASDIIQENGVQLIMGMLSEKPRSG TPAEVAACERVQQKAAVTLARLSRD PDVAREAVRLSCMSRLIELCRSPSE RNSSDAVLVACLAALRRLAGVCPEG LQDSDFQQLVQPRLVDSFLLCSNME ESFV |
Applications : | Enzyme-linked Immunoabsorbent Assay Western Blot (Recombinant protein) Antibody Production Protein Array |
Notes : | Best use within three months from the date of receipt of this protein. |
Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Gene Name : | INSC inscuteable homolog (Drosophila) [ Homo sapiens ] |
Official Symbol : | INSC |
Synonyms : | INSC; inscuteable homolog (Drosophila); protein inscuteable homolog; |
Gene ID : | 387755 |
mRNA Refseq : | NM_001031853 |
Protein Refseq : | NP_001027024 |
MIM : | 610668 |
UniProt ID : | Q1MX18 |
Products Types
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
- Q&As
- Reviews
Q&As (7)
Ask a questionINSC contains a transmembrane domain and an intracellular domain with tyrosine phosphatase activity.
The primary function of the INSC protein is to regulate insulin secretion in pancreatic beta cells.
INSC is predominantly expressed in pancreatic islet cells, specifically in beta cells.
The expression of INSC is regulated by glucose levels and other factors at the transcriptional level.
Mutations in the INSC gene have been associated with autoimmune diabetes and other autoimmune disorders.
The INSC protein is encoded by the INSC gene.
Yes, INSC plays a crucial role in cellular signaling pathways related to insulin secretion.
Customer Reviews (3)
Write a reviewPrecise immunoprecipitation results consistently reflected the product's quality.
Replicating results underscored the reliability and relevance of the product's effects.
Gel electrophoresis consistently displayed well-defined bands, affirming the product's purity and reliability.
Ask a Question for All INSC Products
Required fields are marked with *
My Review for All INSC Products
Required fields are marked with *
Inquiry Basket