Recombinant Human Intelectin 1 (Galactofuranose Binding), FLAG-tagged

• Cat.No.: ITLN1-2176H
• Product Overview: Recombinant Human Intelectin 1 produced inHEK 293was fused at the N-terminus to a FLAG®-tag. Polypeptide chain containing 142 amino acids and having a molecular mass of 30-40 kDa.

Specification

• Species: Human
• Source: HEK293
• Tag: Fc
• Description: Omentin 1 (also named intelectin-1, endothelial lectin HL-1 and intestinal lactoferrin receptor) has been recently identified as a novel visceral fat (or omental fat) depot-specific adipokine. Omentin 1 is a secreted protein of 38kDa containing a fibrinogen-related domain. Omentin 1 is highly expressed in the omental fat, and much less in intestine, lung and heart. Addition of recombinant omentin in vitro did not affect basal, but enhanced insulin-stimulated glucose uptake in subcutaneous as well as in omental human adipocytes. Omentin 1 triggers AKT signalling in the absence of insulin.
• Concentration: 0.1mg/ml after reconstitution.
• Purity: ≥95% (SDS-PAGE)
• Formulation: Lyophilized. Contains PBS.
• Endotoxin Content: <0.1EU/µg purified protein.
• Reconstitution: Reconstitute with 100µl sterile water. PBS containing at least 0.1% BSA should be used for further dilutions.
• Biological Activity: Enhances insulin-mediated glucose transport in 3T3-L1 adipocytes.
• Storage: Short-term storage: +4°C. Long-term storage: -20°C.
• Stability: Stable for at least 6 months after receipt when stored at -20°C.
• Handling: Avoid freeze/thaw cycles. After reconstitution, prepare aliquots and store at -20°C.

Gene Information

• Gene Name: ITLN1 intelectin 1 (galactofuranose binding) [ Homo sapiens ]
• Synonyms: ITLN1; intelectin 1 (galactofuranose binding); HL1; LFR; HL-1; INTL; ITLN; hIntL; omentin; FLJ20022; Intelectin-1; Omentin; Galactofuranose-binding lectin; Intestinal lactoferrin receptor; Endothelial lectin HL-1; OTTHUMP00000027882
• Gene ID: 55600
• mRNA Refseq: NM_017625
• Protein Refseq: NP_060095
• MIM: 609873
• UniProt ID: Q8WWA0
• Chromosome Location: 1q21.3
• Function: receptor binding; sugar binding