Recombinant Human Interferon Regulatory Factor-2, His-tagged

• Cat.No.: IRF2-366H
• Product Overview: Recombinant human IRF2 was expressed in E.coli and purified by using conventional chromatography techniques,15 kDa ( 133 aa).

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Description: Interferon regulatory factor (IRF) 2 is a member of the interferon regulatory transcription factor family. IRF-2 is generally regarded as an oncoprotein. Structure of IRF1 and IRF2 are similar. However, its functions are different. IRF2 competitively inhibits the IRF1-mediated transcriptional activation of interferons alpha and beta, and presumably other genes that employ IRF1 for transcription activation.
• Sequences of amino acids: MGSSHHHHHH SSGLVPRGSH MPVERMRMRP WLEEQINSNT IPGLKWLNKE KKIFQIPWMH AARHGWDVEK DAPLFRNWAI HTGKHQPGVD KPDPKTWKAN FRCAMNSLPD IEEVKDKSIK KGNNAFRVYR MLP
• Formulation: Liquid. In 20mM Tris pH 8.0, 1 mM DTT, 10% glycerol
• Purity: > 95 % by SDS - PAGE
• Concentration: 1 mg/ml (determined by Bradford assay)
• Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.

Gene Information

• Gene Name: IRF2 interferon regulatory factor 2 [ Homo sapiens ]
• Synonyms: DKFZp686F0244; IRF-2; interferon regulatory factor 2; IRF2; Interferon regulatory factor-2
• Gene ID: 3660
• mRNA Refseq: NM_002199
• Protein Refseq: NP_002190
• MIM: 147576
• UniProt ID: P14316
• Chromosome Location: 4q34.1-q35.1
• Function: RNA polymerase II transcription factor activity; protein binding; transcription factor activity