Recombinant Human Interleukin 13 Receptor, Alpha 1 IL13RA1-1650H

Recombinant Human Interleukin 13 Receptor, Alpha 1

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Cat.No. : IL13RA1-1650H Optional Service: Optional requirements on this protein
Description : Interleukin 13 receptor, alpha 1, also known as IL13RA1 and CD213A1 (cluster of differentiation 213A1) is a subunit of the interleukin 13 receptor. This subunit forms a receptor complex with IL4 receptor alpha, a subunit shared by IL13 and IL4 receptors. This subunit serves as a primary IL13-binding subunit of the IL13 receptor, and may also be a component of IL4 receptors. This protein has been shown to bind tyrosine kinase TYK2, and thus may mediate the signaling processes that lead to the activation of JAK1, STAT3 and STAT6 induced by IL13 and IL4. IL-13Ralpha1is essential for allergen-induced airway hyperreactivity and mucus hypersecretion.
Molecular Weight : The predicted molecular weight of Recombinant Human IL-13 Rα1 is Mr 64 kDa. However, the actual molecular weight as observed by migration on SDS Page is Mr 110 kDa.
Source : Mammalian cells
State Of Matter : Lyophilized.
Purity : >90% by SDS Page and analyzed by silver stain.
Endotoxin : <1.0 EU/µg as determined by the LAL method.
Storage And Stability : This lyophilized protein is stable for six to twelve months when stored desiccated at -20℃ to -70℃. After aseptic reconstitution, this protein may be stored at 2℃ to 8℃ for one month or at -20℃ to -70℃ in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions.
Gene Name : IL13RA1 interleukin 13 receptor, alpha 1 [ Homo sapiens ]
Synonyms : IL13RA1; interleukin 13 receptor, alpha 1; NR4; CD213A1; IL-13Ra; CD213a1 antigen; IL13 receptor alpha-1 chain; bB128O4.2.1 (interleukin 13 receptor, alpha 1); CD213a1; CT19; IL-13R-alpha-1; IL-13RA-1; IL13R; OTTHUMP00000023890; Cancer/testis antigen 19
Gene ID : 3597
mRNA Refseq : NM_001560
Protein Refseq : NP_001551
MIM : 300119
UniProt ID : P78552
Chromosome Location : Xq24
Pathway : Cytokine-cytokine receptor interaction; Jak-STAT signaling pathway
Function : interleukin-13 receptor activity; protein binding; receptor activity
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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