Recombinant Human Interleukin 13 Receptor, Alpha 2 IL13RA2-1651H

Recombinant Human Interleukin 13 Receptor, Alpha 2


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Recombinant Human Interleukin 13 Receptor, Alpha 2

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Cat.No. : IL13RA2-1651H Optional Service: Optional requirements on this protein
Description : Interleukin 13 receptor alpha 2, also known as IL13RA2 and CD213A2, binds IL13 with high affinity, but lacks cytoplasmic domain, and does not appear to function as a signal mediator. IL13RA2 serves as a dominant negative inhibitor or a decoy receptor for IL-13. IL-13Ralpha2 is a promising target for ovarian cancer therapy, and the soluble form of IL-13R may be a possible surrogate marker for disease monitoring. IL13RA2 signaling during prolonged inflammation is also an important therapeutic target for the prevention of TGF-beta(1)-mediated fibrosis.
Molecular Weight : The predicted molecular weight of Recombinant Human IL-13 Rα2 is Mr 65 kDa. However, the actual molecular weight as observed by migration on SDS Page is Mr 74 kDa.
Source : Sf 21 Insect Cells.
State Of Matter : Lyophilized.
Purity : >90% by SDS Page and analyzed by silver stain.
Endotoxin : <1.0 EU/µg as determined by the LAL method.
Storage And Stability : This lyophilized protein is stable for six to twelve months when stored desiccated at -20℃ to -70℃. After aseptic reconstitution, this protein may be stored at 2℃ to 8℃ for one month or at -20℃ to -70℃ in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions.
Gene Name : IL13RA2 interleukin 13 receptor, alpha 2 [ Homo sapiens ]
Synonyms : IL13RA2; interleukin 13 receptor, alpha 2; CT19; IL-13R; IL13BP; CD213A2; OTTHUMP00000023871; cancer/testis antigen 19; interleukin 13 binding protein; interleukin 13 receptor alpha 2 chain; IL-13 receptor; CD213a2; IL13R; OTTHUMP00000023871; CD213a2 antigen; Interleukin-13-binding protein
Gene ID : 3598
mRNA Refseq : NM_000640
Protein Refseq : NP_000631
MIM : 300130
UniProt ID : Q14627
Chromosome Location : Xq13.1-q28
Pathway : Jak-STAT signaling pathway
Function : cytokine receptor activity; receptor activity
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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