Recombinant Human INTS10 Protein, GST-tagged

• Cat.No.: INTS10-5089H
• Product Overview: Human INTS10 full-length ORF ( AAH51282.1, 1 a.a. - 597 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: INTS10 is a subunit of the Integrator complex, which associates with the C-terminal domain of RNA polymerase II large subunit (POLR2A; MIM 180660) and mediates 3-prime end processing of small nuclear RNAs U1 (RNU1; MIM 180680) and U2 (RNU2; MIM 180690) (Baillat et al., 2005 [PubMed 16239144]).[supplied by OMIM
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 95.5 kDa
• AA Sequence: MLLKVTEQCFNTLERSEMLLLLLRR FPETVVQHGVGLGEALLEAETIEEQ ESPVNCFRKLFVCDVLPLIINNHDV RLPANLLYKYLNKAAEFYINYVTRS TQIENQHQGAQDTSDLMSPSKRSSQ KYIIEGLTEKSSQIVDPWERLFKIL NVVGMRCEWQMDKGRRSYGDILHRM KDLCRYMNNFDSEAHAKYKNQVVYS TMLVFFKNAFQYVNSIQPSLFQGPN APSQVPLVLLEDVSNVYGDVEIDRN KHIHKKRKLAEGREKTMSSDDEDCS AKGRNRHIVVNKAELANSTEVLESF KLARESWELLYSLEFLDKEFTRICL AWKTDTWLWLRIFLTDMIIYQGQYK KAIASLHHLAALQGSISQPQITGQG TLEHQRALIQLATCHFALGEYRMTC EKVLDLMCYMVLPIQDGGKSQEEPS KVKPKFRKGSDLKLLPCTSKAIMPY CLHLMLACFKLRAFTDNRDDMALGH VIVLLQQEWPRGENLFLKAVNKICQ QGNFQYENFFNYVTNIDMLEEFAYL RTQEGGKIHLELLPNQGMLIKHHTV TRGITKGVKEDFRLAMERQVSRCGE NLMVVLHRFCINEKILLLQTLT
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: INTS10 integrator complex subunit 10 [ Homo sapiens ]
• Official Symbol: INTS10
• Synonyms: INTS10; integrator complex subunit 10; C8orf35, chromosome 8 open reading frame 35; FLJ10569; INT10; C8orf35
• Gene ID: 55174
• mRNA Refseq: NM_018142
• Protein Refseq: NP_060612
• MIM: 611353
• UniProt ID: Q9NVR2