Recombinant Human INTS3 Protein, GST-tagged

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Recombinant Human INTS3 Protein, GST-tagged

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Cat.No. : INTS3-5088H
Product Overview : Human INTS3 full-length ORF ( NP_075391.3, 1 a.a. - 1042 a.a.) recombinant protein with GST-tag at N-terminal.
Description : INTS3 is a subunit of the Integrator complex, which associates with the C-terminal domain of RNA polymerase II large subunit (POLR2A; MIM 180660) and mediates 3-prime end processing of small nuclear RNAs U1 (RNU1; MIM 180680) and U2 (RNU2; MIM 180690) (Baillat et al., 2005 [PubMed 16239144]).[supplied by OMIM
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 144.4 kDa
AA Sequence : MELQKGKGAA AAAAASGAAG GGGGGAGAGA PGGGRLLLST SLDAKDELEE RLERCMSIVT SMTAGVSERE ANDALNAYVC KGLPQHEEIC LGLFTLILTE PAQAQKCYRD LALVSRDGMN IVLNKINQIL MEKYLKLQDT CRTQLVWLVR ELVKSGVLGA DGVCMTFMKQ IAGGDVTAKN IWLAESVLDI LTEQREWVLK SSILIAMAVY TYLRLIVDHH GTAQLQALRQ KEVDFCISLL RERFMECLMI GRDLVRLLQN VARIPEFELL WKDIIHNPQA LSPQFTGILQ LLQSRTSRKF LACRLTPDME TKLLFMTSRV RFGQQKRYQD WFQRQYLSTP DSQSLRCDLI RYICGVVHPS NEVLSSDILP RWAIIGWLLT TCTSNVAASN AKLALFYDWL FFSPDKDSIM NIEPAILVMH HSMKPHPAIT ATLLDFMCRI IPNFYPPLEG HVRQGVFSSL NHIVEKRVLA HLAPLFDNPK LDKELRAMLR EKFPEFCSSP SPPVEVKIEE PVSMEMDNHM SDKDESCYDN AEAAFSDDEE DLNSKGKKRE FRFHPIKETV VEEPVDITPY LDQLDESLRD KVLQLQKGSD TEAQCEVMQE IVDQVLEEDF DSEQLSVLAS CLQELFKAHF RGEVLPEEIT EESLEESVGK PLYLIFRNLC QMQEDNSSFS LLLDLLSELY QKQPKIGYHL LYYLRASKAA AGKMNLYESF AQATQLGDLH TCLMMDMKAC QEDDVRLLCH LTPSIYTEFP DETLRSGELL NMIVAVIDSA QLQELVCHVM MGNLVMFRKD SVLNILIQSL DWETFEQYCA WQLFLAHNIP LETIIPILQH LKYKEHPEAL SCLLLQLRRE KPSEEMVKMV LSRPCHPDDQ FTTSILRHWC MKHDELLAEH IKSLLIKNNS LPRKRQSLRS SSSKLAQLTL EQILEHLDNL RLNLTNTKQN FFSQTPILQA LQHVQASCDE AHKMKFSDLF SLAEEYEDSS TKPPKSRRKA ALSSPRSRKN ATQPPNAEEE SGSSSASEEE DTKPKPTKRK RKGSSAVGSD SD
Applications : Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Quality Control Testing :

12.5% SDS-PAGE Stained with Coomassie Blue

Gene Name : INTS3 integrator complex subunit 3 [ Homo sapiens ]
Official Symbol : INTS3
Synonyms : INTS3; integrator complex subunit 3; C1orf60, chromosome 1 open reading frame 60; FLJ21919; INT3; sensor of single strand DNA complex subunit A; SOSS A; RP11-216N14.4; sensor of ssDNA A; SOSS complex subunit A; sensor of ssDNA subunit A; sensor of single-strand DNA complex subunit A; SOSS-A; C1orf60; C1orf193; FLJ44849; RP11-216N14.2; DKFZp686E1950; DKFZp781I1253; DKFZp686O20115;
Gene ID : 65123
mRNA Refseq : NM_023015
Protein Refseq : NP_075391
MIM : 611347
UniProt ID : Q68E01

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