Recombinant Human INTS3 Protein, GST-tagged

• Cat.No.: INTS3-5088H
• Product Overview: Human INTS3 full-length ORF ( NP_075391.3, 1 a.a. - 1042 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: INTS3 is a subunit of the Integrator complex, which associates with the C-terminal domain of RNA polymerase II large subunit (POLR2A; MIM 180660) and mediates 3-prime end processing of small nuclear RNAs U1 (RNU1; MIM 180680) and U2 (RNU2; MIM 180690) (Baillat et al., 2005 [PubMed 16239144]).[supplied by OMIM
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 144.4 kDa
• AA Sequence: MELQKGKGAAAAAAASGAAGGGGGG AGAGAPGGGRLLLSTSLDAKDELEE RLERCMSIVTSMTAGVSEREANDAL NAYVCKGLPQHEEICLGLFTLILTE PAQAQKCYRDLALVSRDGMNIVLNK INQILMEKYLKLQDTCRTQLVWLVR ELVKSGVLGADGVCMTFMKQIAGGD VTAKNIWLAESVLDILTEQREWVLK SSILIAMAVYTYLRLIVDHHGTAQL QALRQKEVDFCISLLRERFMECLMI GRDLVRLLQNVARIPEFELLWKDII HNPQALSPQFTGILQLLQSRTSRKF LACRLTPDMETKLLFMTSRVRFGQQ KRYQDWFQRQYLSTPDSQSLRCDLI RYICGVVHPSNEVLSSDILPRWAII GWLLTTCTSNVAASNAKLALFYDWL FFSPDKDSIMNIEPAILVMHHSMKP HPAITATLLDFMCRIIPNFYPPLEG HVRQGVFSSLNHIVEKRVLAHLAPL FDNPKLDKELRAMLREKFPEFCSSP SPPVEVKIEEPVSMEMDNHMSDKDE SCYDNAEAAFSDDEEDLNSKGKKRE FRFHPIKETVVEEPVDITPYLDQLD ESLRDKVLQLQKGSDTEAQCEVMQE IVDQVLEEDFDSEQLSVLASCLQEL FKAHFRGEVLPEEITEESLEESVGK PLYLIFRNLCQMQEDNSSFSLLLDL LSELYQKQPKIGYHLLYYLRASKAA AGKMNLYESFAQATQLGDLHTCLMM DMKACQEDDVRLLCHLTPSIYTEFP DETLRSGELLNMIVAVIDSAQLQEL VCHVMMGNLVMFRKDSVLNILIQSL DWETFEQYCAWQLFLAHNIPLETII PILQHLKYKEHPEALSCLLLQLRRE KPSEEMVKMVLSRPCHPDDQFTTSI LRHWCMKHDELLAEHIKSLLIKNNS LPRKRQSLRSSSSKLAQLTLEQILE HLDNLRLNLTNTKQNFFSQTPILQA LQHVQASCDEAHKMKFSDLFSLAEE YEDSSTKPPKSRRKAALSSPRSRKN ATQPPNAEEESGSSSASEEEDTKPK PTKRKRKGSSAVGSDSD
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: INTS3 integrator complex subunit 3 [ Homo sapiens ]
• Official Symbol: INTS3
• Synonyms: INTS3; integrator complex subunit 3; C1orf60, chromosome 1 open reading frame 60; FLJ21919; INT3; sensor of single strand DNA complex subunit A; SOSS A; RP11-216N14.4; sensor of ssDNA A; SOSS complex subunit A; sensor of ssDNA subunit A; sensor of single-strand DNA complex subunit A; SOSS-A; C1orf60; C1orf193; FLJ44849; RP11-216N14.2; DKFZp686E1950; DKFZp781I1253; DKFZp686O20115
• Gene ID: 65123
• mRNA Refseq: NM_023015
• Protein Refseq: NP_075391
• MIM: 611347
• UniProt ID: Q68E01