Recombinant Human INTS7 Protein, GST-tagged

• Cat.No.: INTS7-5085H
• Product Overview: Human INTS7 full-length ORF ( NP_056249.1, 1 a.a. - 962 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: INTS7 is a subunit of the Integrator complex, which associates with the C-terminal domain of RNA polymerase II large subunit (POLR2A; MIM 180660) and mediates 3-prime end processing of small nuclear RNAs U1 (RNU1; MIM 180680) and U2 (RNU2; MIM 180690) (Baillat et al., 2005 [PubMed 16239144]).[supplied by OMIM
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 133.2 kDa
• AA Sequence: MASNSTKSFLADAGYGEQELDANSA LMELDKGLRSGKLGEQCEAVVRFPR LFQKYPFPILINSAFLKLADVFRVG NNFLRLCVLKVTQQSEKHLEKILNV DEFVKRIFSVIHSNDPVARAITLRM LGSLASIIPERKNAHHSIRQSLDSH DNVEVEAAVFAAANFSAQSKDFAVG ICNKISEMIQGLATPVDLKLKLIPI LQHMHHDAILASSARQLLQQLVTSY PSTKMVIVSLHTFTLLAASSLVDTP KQIQLLLQYLKNDPRKAVKRLAIQD LKLLANKTPHTWSRENIQALCECAL QTPYDSLKLGMLSVLSTLSGTIAIK HYFSIVPGNVSSSPRSSDLVKLAQE CCYHNNRGIAAHGVRVLTNITVSCQ EKDLLALEQDAVFGLESLLVLCSQD DSPGAQATLKIALNCMVKLAKGRPH LSQSVVETLLTQLHSAQDAARILMC HCLAAIAMQLPVLGDGMLGDLMELY KVIGRSATDKQQELLVSLATVIFVA SQKALSVESKAVIKQQLESVSNGWT VYRIARQASRMGNHDMAKELYQSLL TQVASEHFYFWLNSLKEFSHAEQCL TGLQEENYSSALSCIAESLKFYHKG IASLTAASTPLNPLSFQCEFVKLRI DLLQAFSQLICTCNSLKTSPPPAIA TTIAMTLGNDLQRCGRISNQMKQSM EEFRSLASRYGDLYQASFDADSATL RNVELQQQSCLLISHAIEALILDPE SASFQEYGSTGTAHADSEYERRMMS VYNHVLEEVESLNRKYTPVSYMHTA CLCNAIIALLKVPLSFQRYFFQKLQ STSIKLALSPSPRNPAEPIAVQNNQ QLALKVEGVVQHGSKPGLFRKIQSV CLNVSSTLQSKSGQDYKIPIDNMTN EMEQRVEPHNDYFSTQFLLNFAILG THNITVESSVKDANGIVWKTGPRTT IFVKSLEDPYSQQIRLQQQQAQQPL QQQQQRNAYTRF
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: INTS7 integrator complex subunit 7 [ Homo sapiens ]
• Official Symbol: INTS7
• Synonyms: INTS7; integrator complex subunit 7; C1orf73, chromosome 1 open reading frame 73; DKFZP434B168; INT7; C1orf73; DKFZp434B168
• Gene ID: 25896
• mRNA Refseq: NM_001199809
• Protein Refseq: NP_001186738
• MIM: 611350
• UniProt ID: Q9NVH2