Recombinant Human IRF1 protein(1-325aa), His&Myc-tagged

• Cat.No.: IRF1-1833H
• Product Overview: Recombinant Human IRF1 protein(P10914)(1-325aa), fused with N-terminal His tag and C-terminal Myc tag, was expressed in E.coli.

Specification

• Source: E.coli
• Species: Human
• Tag: N-His&C-Myc
• Protein length: 1-325aa
• Form: If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.
• Molecular Mass: 44.0 kDa
• AASequence: MPITRMRMRPWLEMQINSNQIPGLI WINKEEMIFQIPWKHAAKHGWDINK DACLFRSWAIHTGRYKAGEKEPDPK TWKANFRCAMNSLPDIEEVKDQSRN KGSSAVRVYRMLPPLTKNQRKERKS KSSRDAKSKAKRKSCGDSSPDTFSD GLSSSTLPDDHSSYTVPGYMQDLEV EQALTPALSPCAVSSTLPDWHIPVE VVPDSTSDLYNFQVSPMPSTSEATT DEDEEGKLPEDIMKLLEQSEWQPTN VDGKGYLLNEPGVQPTSVYGDFSCK EEPEIDSPGGDIGLSLQRVFTDLKN MDATWLDSLLTPVRLPSIQAIPCAP
• Purity: Greater than 85% as determined by SDS-PAGE.
• Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
• Reconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C.

Gene Information

• Gene Name: IRF1 interferon regulatory factor 1 [ Homo sapiens ]
• Official Symbol: IRF1
• Synonyms: IRF1; interferon regulatory factor 1; MAR; IRF-1
• Gene ID: 3659
• mRNA Refseq: NM_002198
• Protein Refseq: NP_002189
• MIM: 147575
• UniProt ID: P10914

Reviews

10/19/2021

Swift protein expression optimization, boosts our research productivity.

05/03/2020

Accurate protein structural characterization, a cornerstone of our studies.

11/01/2019

High-quality protein sequencing, invaluable for our scientific work.

Q&As

How do changes in IRF1 expression or function affect responses to bacterial infections?

Variations in IRF1 impact the body's response to bacterial infections.

How does IRF1 impact the pathogenesis of autoimmune diseases?

IRF1 may play a key role in the development of autoimmune diseases.

What role does IRF1 play in antiviral defense mechanisms?

IRF1 is crucial in antiviral defenses, enhancing response to viral infections.

How does IRF1 regulate gene expression in the immune response?

IRF1 activates immune response genes, especially interferon-responsive genes.

What is the effect of IRF1 on tumor suppression and cancer cell proliferation?

IRF1 acts as a tumor suppressor, inhibiting cancer cell growth.

How does IRF1 influence the development and function of T cells and NK cells?

IRF1 affects the development and function of T cells and NK cells.

How does IRF1 modulate inflammatory responses and cytokine production?

IRF1 regulates inflammation and cytokine production.