Recombinant Human IRF4 Protein, GST-His-tagged


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Recombinant Human IRF4 Protein, GST-His-tagged

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Cat.No. : IRF4-726H
Product Overview : Recombinant Human IRF4, transcript variant 1, fused with N-terminal GST and C-terminal His was expressed in E. coli.
Description : The protein encoded by this gene belongs to the IRF (interferon regulatory factor) family of transcription factors, characterized by an unique tryptophan pentad repeat DNA-binding domain. The IRFs are important in the regulation of interferons in response to infection by virus, and in the regulation of interferon-inducible genes. This family member is lymphocyte specific and negatively regulates Toll-like-receptor (TLR) signaling that is central to the activation of innate and adaptive immune systems. A chromosomal translocation involving this gene and the IgH locus, t(6;14)(p25;q32), may be a cause of multiple myeloma. Alternatively spliced transcript variants have been found for this gene.
Source : E. coli
Species : Human
Tag : GST-His
Form : 25mM Tris, pH8.0, 150mM NaCl, 10% glycerol, 1% Sarkosyl.
Molecular Mass : 79.6kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration : >50 ug/mL as determined by microplate BCA method
Gene Name : IRF4 interferon regulatory factor 4 [ Homo sapiens ]
Official Symbol : IRF4
Synonyms : IRF4; interferon regulatory factor 4; MUM1; LSIRF; multiple myeloma oncogene 1; lymphocyte-specific interferon regulatory factor; NF-EM5;
Gene ID : 3662
mRNA Refseq : NM_001195286
Protein Refseq : NP_001182215
MIM : 601900
UniProt ID : Q15306

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