Recombinant Human IRGM Protein, GST-tagged

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Recombinant Human IRGM Protein, GST-tagged

IRGM Related Products

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Cat.No. : IRGM-5030H
Product Overview : Human IRGM partial ORF ( XP_293893.3, 99 a.a. - 181 a.a.) recombinant protein with GST-tag at N-terminal.
Description : Members of the p47 immunity-related GTPase (IRG) family, including IRGM, play an important role in the murine immune system; however, in humans this resistance system is greatly reduced. There is evidence that human IRGM plays a role in autophagy and control of intracellular mycobacteria (Bekpen et al., 2005; Singh et al., 2006 [PubMed 16888103]).[supplied by OMIM
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 34.87 kDa
AA Sequence : TTLENYLMEM QFNRYDFIMV ASAQFSMNHV MLAKTAEDMG KKFYIVWTKL DMDLSTGALP EVQLLQIREN VLENLQKERV CEY
Applications : Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Quality Control Testing :

12.5% SDS-PAGE Stained with Coomassie Blue

Gene Name : IRGM immunity-related GTPase family, M [ Homo sapiens ]
Official Symbol : IRGM
Synonyms : IRGM; immunity-related GTPase family, M; immunity related GTPase family, M1 , IRGM1; immunity-related GTPase family M protein; IFI1; LRG 47; LRG47; LRG-47-like protein; interferon-inducible protein 1; immunity-related GTPase family, M1; LPS-stimulated RAW 264.7 macrophage protein 47 homolog; IRGM1; LRG-47; MGC149263; MGC149264;
Gene ID : 345611
mRNA Refseq : NM_001145805
Protein Refseq : NP_001139277
MIM : 608212
UniProt ID : A1A4Y4

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