Recombinant Human ITGA5 & ITGB1 protein, His-Avi-tagged

• Cat.No.: ITGA5 & ITGB1-567H
• Product Overview: Human ITGA5&ITGB1 Heterodimer Protein is expressed from mammalian with a His Tag and Avi Tag at the C-terminal. It contains Phe42-Tyr995 (P08648) acidic tail& Gln21-His 728 (P05556) basic tail.

Specification

• Description: Integrin alpha 5/ beta 1, also known as VLA-5, is a widely expressed non-covalent heterodimer of a 160 kDa alpha 5 and a 130 kDa beta 1 Integrin subunit. Alpha 5/ beta 1 is up‑regulated on tumor vasculature and promotes angiogenesis.
• Source: HEK293
• Species: Human
• Tag: His-Avi
• Form: Supplied as 0. 22um filtered solution in 20mMPB,150mMNaCl (pH 7. 4).
• Molecular Mass: The protein has a predicted MW of 111. 8 kDa (P08648) & 83. 2 kDa (P05556). Due to glycosylation, the protein migrates to 100-140KDa based on Bis-Tris PAGE result.
• Protein length: It contains Phe42-Tyr995 (P08648) acidic tail& Gln21-His 728 (P05556) basic tail.
• Endotoxin: Less than 0. 01EU per ug by the LAL method.
• Purity: > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
• Storage: The product should be stored at -70°C. Please do not repeated freeze-thaw cycles.
• Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4℃ before opening to recover the entire contents.

Gene Information

• Gene Name: ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide) [ Homo sapiens ]
• Official Symbol: ITGA5; ITGB1
• Synonyms: Integrin alpha 5 beta 1; VLA-5
• Gene ID: 3678
• mRNA Refseq: NM_002205
• Protein Refseq: NP_002196
• MIM: 135620
• UniProt ID: P08648