| Description : |
The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha subunit and a beta subunit that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 5 subunit. This subunit associates with the beta 1 subunit to form a fibronectin receptor. This integrin may promote tumor invasion, and higher expression of this gene may be correlated with shorter survival time in lung cancer patients. Note that the integrin alpha 5 and integrin alpha V subunits are encoded by distinct genes. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
114.5 kDa |
| AA Sequence : |
MGSRTPESPLHAVQLRWGPRRRPPL LPLLLLLLPPPPRVGGFNLDAEAPA VLSGPPGSFFGFSVEFYRPGTDGVS VLVGAPKANTSQPGVLQGGAVYLCP WGASPTQCTPIEFDSKGSRLLESSL SSSEGEEPVEYKSLQWFGATVRAHG SSILACAPLYSWRTEKEPLSDPVGT CYLSTDNFTRILEYAPCRSDFSWAA GQGYCQGGFSAEFTKTGRVVLGGPG SYFWQGQILSATQEQIAESYYPEYL INLVQGQLQTRQASSIYDDSYLGYS VAVGEFSGDDTEDFVAGVPKGNLTY GYVTILNGSDIRSLYNFSGEQMASY FGYAVAATDVNGDGLDDLLVGAPLL MDRTPDGRPQEVGRVYVYLQHPAGI EPTPTLTLTGHDEFGRFGSSLTPLG DLDQDGYNDVAIGAPFGGETQQGVV FVFPGGPGGLGSKPSQVLQPLWAAS HTPDFFGSALRGGRDLDGNGYPDLI VGSFGVDKAVVYRGRPIVSASASLT IFPAMFNPEERSCSLEGNPVACINL SFCLNASGKHVADSIGFTVELQLDW QKQKGGVRRALFLASRQATLTQTLL IQNGAREDCREMKIYLRNESEFRDK LSPIHIALNFSLDPQAPVDSHGLRP ALHYQSKSRIEDKAQILLDCGEDNI CVPDLQLEVFGEQNHVYLGDKNALN LTFHAQNVGEGGAYEAELRVTAPPE AEYSGLVRHPGNFSSLSCDYFAVNQ SRLLVCDLGNPMKAGASLWGGLRFT VPHLRDTKKTIQFDFQILSKNLNNS QSDVVSFRLSVEAQAQVTLNGVSKP EAVLFPVSDWHPRDQPQKEEDLGPA VHHVYELINQGPSSISQGVLELSCP QALEGQQLLYVTRVTGLNCTTNHPI NPKGLELDPEGSLHHQQKREAPSRS SASSGPQILKCPEAECFRLRCELGP LHQQESQSLQLHFRVWAKTFLQREH QPFSLQCEAVYKALKMPYRILPRQL PQKERQVATAVQWTKAEGSYGVPLW IIILAILFGLLLLGLLIYILYKLGF FKRSLPYGTAMEKAQLKPPATSDAT RTRPLEQKLISEEDLAANDILDYKD DDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
