Recombinant Human ITGB2 Protein, GST-tagged

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Recombinant Human ITGB2 Protein, GST-tagged

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Cat.No. : ITGB2-4978H
Product Overview : Human ITGB2 full-length ORF ( AAH05861, 1 a.a. - 769 a.a.) recombinant protein with GST-tag at N-terminal.
Description : The product of this gene belongs to the integrin beta chain family of proteins. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. This gene encodes the integrin beta chain beta 2. A given chain may combine with multiple partners resulting in different integrins. For example, beta 2 combines with the alpha L chain to form the integrin LFA-1, and combines with the alpha M chain to form the integrin Mac-1. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling. Defects in this gene are the cause of leukocyte adhesion deficiency type I (LAD1). Two transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 110.33 kDa
AA Sequence : MLGLRPPLLALVGLL SLGCALSQECTKFKV SSCRECIESGPGCTW CQKLNFTGPGDPDSI RCDTRPQLLMRGCAA DDIMDPTSLAETQED HNGGQKQLSPQKVTL YLRPGQAAAFNVTFR RAKGYPIDLYYLMDL SYSMLDDLRNVKKLG GDLLRALNEITESGR IGFGSFVDKTVLPFV NTHPDKLRNPCPNKE KECQPPFAFRHVLKL TNNSNQFQTEVGKQL ISGNLDAPEGGLDAM MQVAACPEEIGWRNV TRLLVFATDDGFHFA GDGKLGAILTPNDGR CHLEDNLYKRSNEFD YPSVGQLAHKLAENN IQPIFAVTSRMVKTY EKLTEIIPKSAVGEL SEDSSNVVHLIKNAY NKLSSRVFLDHNALP DTLKVTYDSFCSNGV THRNQPRGDCDGVQI NVPITFQVKVTATEC IQEQSFVIRALGFTD IVTVQVLPQCECRCR DQSRDRSLCHGKGFL ECGICRCDTGYIGKN CECQTQGRSSQELEG SCRKDNNSIICSGLG DCVCGQCLCHTSDVP GKLIYGQYCECDTIN CERYNGQVCGGPGRG LCFCGKCRCHPGFEG SACQCERTTEGCLNP RRVECSGRGRCRCNV CECHSGYQLPLCQEC PGCPSPCGKYISCAE CLKFEKGPFGKNCSA ACPGLQLSNNPVKGR TCKERDSEGCWVAYT LEQQDGMDRYLIYVD ESRECVAGPNIAAIV GGTVAGIVLIGILLL VIWKALIHLSDLREY RRFEKEKLKSQWNND NPLFKSATTTVMNPK FAES
Applications : Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Quality Control Testing :

12.5% SDS-PAGE Stained with Coomassie Blue

Gene Name : ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) [ Homo sapiens ]
Official Symbol : ITGB2
Synonyms : ITGB2; integrin, beta 2 (complement component 3 receptor 3 and 4 subunit); CD18, integrin, beta 2 (antigen CD18 (p95), lymphocyte function associated antigen 1; macrophage antigen 1 (mac 1) beta subunit) , MFI7; integrin beta-2; LFA 1; MAC 1; integrin beta chain, beta 2; complement receptor C3 beta-subunit; complement receptor C3 subunit beta; leukocyte cell adhesion molecule CD18; leukocyte-associated antigens CD18/11A, CD18/11B, CD18/11C; cell surface adhesion glycoproteins LFA-1/CR3/p150,95 subunit beta; cell surface adhesion glycoprotein LFA-1/CR3/P150,959 beta subunit precursor); LAD; CD18; MF17; MFI7; LCAMB; LFA-1; MAC-1;
Gene ID : 3689
mRNA Refseq : NM_000211
Protein Refseq : NP_000202
MIM : 600065
UniProt ID : P05107

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