| Description : |
This gene encodes a member of the inositol 1,4,5-trisphosphate [Ins(1,4,5)P(3)] 3-kinase family of enzymes that catalyze the phosphorylation of inositol 1,4,5-trisphosphate to 1,3,4,5-tetrakisphosphate. The encoded protein is localized to the nucleus and cytoplasm and has both nuclear import and nuclear export activity. Single nucleotide polymorphisms in this gene are associated with Kawasaki disease. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
75.2 kDa |
| AA Sequence : |
MRRCPCRGSLNEAEAGALPAAARMG LEAPRGGRRRQPGQQRPGPGAGAPA GRPEGGGPWARTEGSSLHSEPERAG LGPAPGTESPQAEFWTDGQTEPAAA GLGVETERPKQKTEPDRSSLRTHLE WSWSELETTCLWTETGTDGLWTDPH RSDLQFQPEEASPWTQPGVHGPWTE LETHGSQTQPERVKSWADNLWTHQN SSSLQTHPEGACPSKEPSADGSWKE LYTDGSRTQQDIEGPWTEPYTDGSQ KKQDTEAARKQPGTGGFQIQQDTDG SWTQPSTDGSQTAPGTDCLLGEPED GPLEEPEPGELLTHLYSHLKCSPLC PVPRLIITPETPEPEAQPVGPPSRV EGGSGGFSSASSFDESEDDVVAGGG GASDPEDRSGSKPWKKLKTVLKYSP FVVSFRKHYPWVQLSGHAGNFQAGE DGRILKRFCQCEQRSLEQLMKDPLR PFVPAYYGMVLQDGQTFNQMEDLLA DFEGPSIMDCKMGSRTYLEEELVKA RERPRPRKDMYEKMVAVDPGAPTPE EHAQGAVTKPRYMQWRETMSSTSTL GFRIEGIKKADGTCNTNFKKTQALE QVTKVLEDFVDGDHVILQKYVACLE ELREALEISPFFKTHEVVGSSLLFV HDHTGLAKVWMIDFGKTVALPDHQT LSHRLPWAEGNREDGYLWGLDNMIC LLQGLAQSTRTRPLEQKLISEEDLA ANDILDYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
