Recombinant Human JAGN1 Protein (M1-K183), 10×His tagged

• Cat.No.: JAGN1-0453H
• Product Overview: Recombinant Human sfGFP(M1-N144)-JAGN1(M1-K183 end)-sfGFP(N146-T230)-10His Protein was expressed in Mammalian cell.

Specification

• Description: Endoplasmic reticulum transmembrane protein involved in vesicle-mediated transport, which is required for neutrophil function. Required for vesicle-mediated transport; it is however unclear whether it is involved in early secretory pathway or intracellular protein transport. Acts as a regulator of neutrophil function, probably via its role in vesicle-mediated transport: required for defense against fungal pathogens and for granulocyte colony-stimulating factor (GM-CSF) signaling pathway; possibly by regulating glycosylation and/or targeting of proteins contributing to the viability and migration of neutrophils.
• Source: Mammalian cell
• Species: Human
• Tag: 10His
• Form: Liquid
• Protein Length: M1-K183
• Endotoxin: < 0.01 EU per μg of the protein
• Purity: 70%
• Stability: Samples are stable for up to twelve months from date of receipt at -20 to -80 centigrade.
• Storage: Store it under sterile conditions at -20 to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Storage Buffer: 20 mM Tris-HCl (pH 8.0), 150 mM NaCl, 0.02% LMNG
• Shipping: It is shipped out with blue ice.

Gene Information

• Gene Name: JAGN1 jagunal homolog 1 (Drosophila) [ Homo sapiens (human) ]
• Official Symbol: JAGN1
• Synonyms: JAGN1; jagunal homolog 1 (Drosophila); protein jagunal homolog 1; FLJ14602; GL009
• Gene ID: 84522
• mRNA Refseq: NM_032492
• Protein Refseq: NP_115881
• UniProt ID: Q8N5M9