Recombinant Human KARS, His-tagged
Cat.No. : | KARS-1010H |
Product Overview : | Recombinant human KARS protein, fused to His-tag at N-terminus, was expressed in E.coliand purified by using conventional chromatography. |
- Specification
- Gene Information
- Related Products
Cat. No. : | KARS-1010H |
Description : | KARS, also known as Lysyl-tRNAsynthetase, belongs to the class-II aminoacyl-tRNAsynthetase family. It exists as both mitochondrial and cytoplasmic isoforms produced by alternative splicing, and thought to play a role in autoimmune diseases, such as polymyositis or dermatomyositis. This protein functions to catalyze the aminoacylation of tRNAs by their corresponding amino acids, thus linking amino acids with tRNA-contained nucleotide triplets. |
Form : | Liquid. 20mM Tris-HCl buffer (pH8.0) containing 20% glycerol, 0.1M NaCl,1mM DTT |
Molecular Weight : | 63.7 kDa (558aa) |
Purity : | > 95% by SDS - PAGE |
Concentration : | 1.0 mg/ml (determined by Bradford assay) |
Sequences of amino acids : | MGSSHHHHHH SSGLVPRGSH MGSGVGPEEE SVDPNQYYKI RSQAIHQLKV NGEDPYPHKF HVDISLTDFI QKYSHLQPGD HLTDITLKVAGRIHAKRASG GKLIFYDLRG EGVKLQVMAN SRNYKSEEEF IHINNKLRRG DIIGVQGNPG KTKKGELSII PYEITLLSPC LHMLPHLHFGLKDKETRYRQ RYLDLILNDF VRQKFIIRSK IITYIRSFLD ELGFLEIETP MMNIIPGGAV AKPFITYHNE LDMNLYMRIA PELYHKMLVVGGIDRVYEIG RQFRNEGIDL THNPEFTTCE FYMAYADYHD LMEITEKMVS GMVKHITGSY KVTYHPDGPE GQAYDVDFTP PFRRINMVEELEKALGMKLP ETNLFETEET RKILDDICVA KAVECPPPRT TARLLDKLVG EFLEVTCINP TFICDHPQIM SPLAKWHRSK EGLTERFELFVMKKEICNAY TELNDPMRQR QLFEEQAKAK AAGDDEAMFI DENFCTALEY GLPPTAGWGM GIDRVAMFLT DSNNIKEVLL FPAMKPEDKKENVATTDTLE STTVGTSV |
Storage : | Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C.Avoid repeated freezing and thawing cycles. |
Gene Name : | KARS lysyl-tRNA synthetase [ Homo sapiens ] |
Official Symbol : | KARS |
Synonyms : | KARS; KRS; KARS2; CMTRIB; KIAA0070; lysyl-tRNAsynthetase;lysRS; OTTHUMP00000174948; OTTHUMP00000174949; lysine tRNA ligase; EC 6.1.1.6; Lysine--tRNA ligase |
Gene ID : | 3735 |
mRNA Refseq : | NM_001130089 |
Protein Refseq : | NP_001123561 |
MIM : | 601421 |
UniProt ID : | Q15046 |
Chromosome Location : | 16q23.1 |
Function : | ATP binding; ligase activity; lysine-tRNA ligase activity; metal ion binding; nucleic acid binding; nucleotide binding; tRNA binding |
Products Types
◆ Recombinant Protein | ||
Kars-3642M | Recombinant Mouse Kars Protein, Myc/DDK-tagged | +Inquiry |
KARS-2159R | Recombinant Rhesus Macaque KARS Protein, His (Fc)-Avi-tagged | +Inquiry |
KARS-527Z | Recombinant Zebrafish KARS | +Inquiry |
KARS-2296C | Recombinant Chicken KARS | +Inquiry |
KARS-2338R | Recombinant Rhesus monkey KARS Protein, His-tagged | +Inquiry |
◆ Lysates | ||
KARS-5090HCL | Recombinant Human KARS 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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