Recombinant Human KARS1 Protein (Arg323-Arg553), N-His tagged

• Cat.No.: KARS1-3384H
• Product Overview: Recombinant human KARS1 (Arg323-Arg553) protein fused with the N-His tag was expressed in E. coli.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: Arg323-Arg553
• Description: Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. Lysyl-tRNA synthetase is a homodimer localized to the cytoplasm which belongs to the class II family of tRNA synthetases. It has been shown to be a target of autoantibodies in the human autoimmune diseases, polymyositis or dermatomyositis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
• Molecular Mass: 28.80 kDa
• Purity: >90 % as determined by SDS-PAGE.
• Notes: For research use only.
• Storage: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 centigrade for one week. Store at -20 to -80 centigrade for twelve months from the date of receipt.
• Storage Buffer: 0.01M PBS, pH 7.4, 0.02 % NLS
• Reconstitution: Reconstitute in sterile water for a stock solution.
• Shipping: In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.

Gene Information

• Gene Name: KARS1 lysyl-tRNA synthetase 1 [ Homo sapiens (human) ]
• Official Symbol: KARS1
• Synonyms: KARS1; lysyl-tRNA synthetase 1; KRS; KARS; KARS2; LEPID; CMTRIB; DEAPLE; DFNB89; lysine--tRNA ligase; lysRS; lysine tRNA ligase; EC 6.1.1.6
• Gene ID: 3735
• mRNA Refseq: NM_005548
• Protein Refseq: NP_005539
• MIM: 601421
• UniProt ID: Q15046