Recombinant Human KATNA1 Protein (Met1-Gly168), His tagged

• Cat.No.: KATNA1-2910H
• Product Overview: Recombinant human KATNA1 (Met1-Gly168) protein fused with His tag was expressed in E. coli.

Specification

• Description: Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Microtubule release from the mitotic spindle poles may allow depolymerization of the microtubule end proximal to the spindle pole, leading to poleward microtubule flux and poleward motion of chromosome. Microtubule release within the cell body of neurons may be required for their transport into neuronal processes by microtubule-dependent motor proteins. This transport is required for axonal growth.
• Source: E. coli
• Species: Human
• Tag: His
• Molecular Mass: 21.31 kDa
• Protein Length: Met1-Gly168
• Purity: >90 % as determined by SDS-PAGE.
• Notes: For research use only.
• Storage: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 centigrade for one week. Store at -20 to -80 centigrade for twelve months from the date of receipt.
• Storage Buffer: Supplied as solution form in PBS pH 7.5 or lyophilized from PBS pH 7.5.
• Reconstitution: Reconstitute in sterile water for a stock solution.
• Shipping: In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.

Gene Information

• Gene Name: KATNA1 katanin p60 (ATPase containing) subunit A 1 [ Homo sapiens (human) ]
• Official Symbol: KATNA1
• Synonyms: KATNA1; katanin p60 (ATPase containing) subunit A 1; katanin p60 ATPase-containing subunit A1; p60 katanin; katanin p60 subunit A1; katanin p60 (ATPase-containing) subunit A 1
• Gene ID: 11104
• mRNA Refseq: NM_001204076
• Protein Refseq: NP_001191005
• MIM: 606696
• UniProt ID: O75449