| Description : |
The protein encoded by this gene is a transcriptional activator, having been shown to increase the transcription of activator protein-1 and serum response element. The encoded protein can also form a complex with KBTBD6 and CUL3, which regulates the ubiquitylation and degradation of TIAM1, which is a regulator of RAC1. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
77.2 kDa |
| AA Sequence : |
MQSREDVPRSRRLASPRGGRRPKRI SKPSVSAFFTGPEELKDTAHSAALL AQLKSFYDARLLCDVTIEVVTPGSG PGTGRLFSCNRNVLAAACPYFKSMF TGGMYESQQASVTMHDVDAESFEVL VDYCYTGRVSLSEANVQRLYAASDM LQLEYVREACASFLARRLDLTNCTA ILKFADAFDHHKLRSQAQSYIAHNF KQLSRMGSIREETLADLTLAQLLAV LRLDSLDIESERTVCHVAVQWLEAA AKERGPSAAEVFKCVRWMHFTEEDQ DYLEGLLTKPIVKKYCLDVIEGALQ MRYGDLLYKSLVPVPNSSSSSSSSN SLVSAAENPPQRLGMCAKEMVIFFG HPRDPFLCYDPYSGDIYTMPSPLTS FAHTKTVTSSAVCVSPDHDIYLAAQ PRKDLWVYKPAQNSWQQLADRLLCR EGMDVAYLNGYIYILGGRDPITGVK LKEVECYSVQRNQWALVAPVPHSFY SFELIVVQNYLYAVNSKRMLCYDPS HNMWLNCASLKRSDFQEACVFNDEI YCICDIPVMKVYNPARGEWRRISNI PLDSETHNYQIVNHDQKLLLITSTT PQWKKNRVTVYEYDTREDQWINIGT MLGLLQFDSGFICLCARVYPSCLEP GQSFITEEDDARSESSTEWDLDGFS ELDSESGSSSSFSDDEVWVQVAPQR NAQDQQGSLTRTRPLEQKLISEEDL AANDILDYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
