Recombinant Human KCNAB2 protein, Myc/DDK-tagged

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Recombinant Human KCNAB2 protein, Myc/DDK-tagged

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Cat.No. : KCNAB2-22H
Product Overview : Recombinant Human KCNAB2 protein transcript variant 1, fused to Myc/DDK-tag at C-terminus, was expressed in human 293 cells (HEK293).
Description : Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member is one of the beta subunits, which are auxiliary proteins associating with functional Kv-alpha subunits. This member alters functional properties of the KCNA4 gene product. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms.
Source : HEK293
Species : Human
Tag : Myc/DDK
Form : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Molecular Mass : 40.8 kDa
Purity : >80% as determined by SDS-PAGE and Coomassie blue staining
Concentration : >50 μg/mL as determined by microplate BCA method
Gene Name : KCNAB2
Official Symbol : KCNAB2
Synonyms : KCNAB2; potassium voltage-gated channel, shaker-related subfamily, beta member 2; voltage-gated potassium channel subunit beta-2; AKR6A5; HKvbeta2.1; HKvbeta2.2; KCNA2B; K+ channel beta-2 subunit; K(+) channel subunit beta-2; potassium channel shaker chain beta 2; HKvbeta2; KV-BETA-2; MGC117289;
Gene ID : 8514
mRNA Refseq : NM_001199860
Protein Refseq : NP_001186789
MIM : 601142
UniProt ID : Q13303
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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