Recombinant Human KCNJ6 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: KCNJ6-1559H
• Product Overview: KCNJ6 MS Standard C13 and N15-labeled recombinant protein (NP_002231) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: This gene encodes a member of the G protein-coupled inwardly-rectifying potassium channel family of inward rectifier potassium channels. This type of potassium channel allows a greater flow of potassium into the cell than out of it. These proteins modulate many physiological processes, including heart rate in cardiac cells and circuit activity in neuronal cells, through G-protein coupled receptor stimulation. Mutations in this gene are associated with Keppen-Lubinsky Syndrome, a rare condition characterized by severe developmental delay, facial dysmorphism, and intellectual disability.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 48.5 kDa
• AA Sequence: MAKLTESMTNVLEGDSMDQDVESPV AIHQPKLPKQARDDLPRHISRDRTK RKIQRYVRKDGKCNVHHGNVRETYR YLTDIFTTLVDLKWRFNLLIFVMVY TVTWLFFGMIWWLIAYIRGDMDHIE DPSWTPCVTNLNGFVSAFLFSIETE TTIGYGYRVITDKCPEGIILLLIQS VLGSIVNAFMVGCMFVKISQPKKRA ETLVFSTHAVISMRDGKLCLMFRVG DLRNSHIVEASIRAKLIKSKQTSEG EFIPLNQTDINVGYYTGDDRLFLVS PLIISHEINQQSPFWEISKAQLPKE ELEIVVILEGMVEATGMTCQARSSY ITSEILWGYRFTPVLTLEDGFYEVD YNSFHETYETSTPSLSAKELAELAS RAELPLSWSVSSKLNQHAELETEEE EKNLEEQTERNGDVANLENESKVTR TRPLEQKLISEEDLAANDILDYKDD DDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: KCNJ6 potassium inwardly rectifying channel subfamily J member 6 [ Homo sapiens (human) ]
• Official Symbol: KCNJ6
• Synonyms: KCNJ6; potassium inwardly-rectifying channel, subfamily J, member 6; KCNJ7; G protein-activated inward rectifier potassium channel 2; BIR1; GIRK2; hiGIRK2; KATP2; Kir3.2; inward rectifier K(+) channel Kir3.2; inward rectifier potassium channel KIR3.2; potassium channel, inwardly rectifying subfamily J member 6; GIRK-2; KATP-2; KIR3.2; MGC126596
• Gene ID: 3763
• mRNA Refseq: NM_002240
• Protein Refseq: NP_002231
• MIM: 600877
• UniProt ID: P48051