| Description : |
This gene is a member of the Jumonji domain 2 (JMJD2) family and encodes a protein containing a JmjN domain, a JmjC domain, a JD2H domain, two TUDOR domains, and two PHD-type zinc fingers. This nuclear protein functions as a trimethylation-specific demethylase, converting specific trimethylated histone residues to the dimethylated form, and as a transcriptional repressor. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
120.7 kDa |
| AA Sequence : |
MASESETLNPSARIMTFYPTMEEFR NFSRYIAYIESQGAHRAGLAKVVPP KEWKPRASYDDIDDLVIPAPIQQLV TGQSGLFTQYNIQKKAMTVREFRKI ANSDKYCTPRYSEFEELERKYWKNL TFNPPIYGADVNGTLYEKHVDEWNI GRLRTILDLVEKESGITIEGVNTPY LYFGMWKTSFAWHTEDMDLYSINYL HFGEPKSWYSVPPEHGKRLERLAKG FFPGSAQSCEAFLRHKMTLISPLML KKYGIPFDKVTQEAGEFMITFPYGY HAGFNHGFNCAESTNFATRRWIEYG KQAVLCSCRKDMVKISMDVFVRKFQ PERYKLWKAGKDNTVIDHTLPTPEA AEFLKESELPPRAGNEEECPEEDME GVEDGEEGDLKTSLAKHRIGTKRHR VCLEIPQEVSQSELFPKEDLSSEQY EMTECPAALAPVRPTHSSVRQVEDG LTFPDYSDSTEVKFEELKNVKLEEE DEEEEQEAAALDLSVNPASVGGRLV FSGSKKKSSSSLGSGSSRDSISSDS ETSEPLSCRAQGQTGVLTVHSYAKG DGRVTVGEPCTRKKGSAARSFSERE LAEVADEYMFSLEENKKSKGRRQPL SKLPRHHPLVLQECVSDDETSEQLT PEEEAEETEAWAKPLSQLWQNRPPN FEAEKEFNETMAQQAPHCAVCMIFQ TYHQVEFGGFNQNCGNASDLAPQKQ RTKPLIPEMCFTSTGCSTDINLSTP YLEEDGTSILVSCKKCSVRVHASCY GVPPAKASEDWMCSRCSANALEEDC CLCSLRGGALQRANDDRWVHVSCAV AILEARFVNIAERSPVDVSKIPLPR FKLKCIFCKKRRKRTAGCCVQCSHG RCPTAFHVSCAQAAGVMMQPDDWPF VVFITCFRHKIPNLERAKGALQSIT AGQKVISKHKNGRFYQCEVVRLTTE TFYEVNFDDGSFSDNLYPEDIVSQD CLQFGPPAEGEVVQVRWTDGQVYGA KFVASHPIQMYQVEFEDGSQLVVKR DDVYTLDEELPKRVKSRLSVASDMR FNEIFTEKEVKQEKKRQRVINSRYR EDYIEPALYRAIMETRTRPLEQKLI SEEDLAANDILDYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
