Recombinant Human KDR Protein, Fc-tagged, FITC conjugated
Cat.No. : | KDR-31716THF |
Product Overview : | FITC conjugated recombinant fragment: human soluble Vascular Endothelial Growth Factor Receptor 2 (sVEGFR2) was fused with the Fc part of human IgG1 and expressed in Insect cells. The recombinantsVEGFR2/Fc is a disulfide-linked homodimeric protein, M.Wt of themonomer is |
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Description : | Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, T-cell protein tyrosine phosphatase, etc.. Mutations of this gene are implicated in infantile capillary hemangiomas. |
Source : | Insect cells |
Species : | Human |
Tag : | Fc |
Form : | Lyophilized |
Purity : | > 90 % as determined by SDS-PAGE |
Characteristic : | Disulfide-linked homodimer Labeled with FITC via amines Excitation source: 488 nm spectral line, argon-ion laser Excitation Wavelength: 488 nm Emission Wavelength: 535 nm |
Storage : | Shipped at 4 centigrade. Upon delivery aliquot and store at -20 or -80 centigrade. Avoid repeated freeze/thaw cycles. |
Storage Buffer : | PBS, pH 7.4 |
Reconstitution : | PBS or medium to a concentration not lower than 50 μg/mL. |
Gene Name : | KDR kinase insert domain receptor (a type III receptor tyrosine kinase) [ Homo sapiens ] |
Official Symbol : | KDR |
Synonyms : | KDR; kinase insert domain receptor (a type III receptor tyrosine kinase); vascular endothelial growth factor receptor 2; CD309; FLK1; VEGFR; VEGFR2; |
Gene ID : | 3791 |
mRNA Refseq : | NM_002253 |
Protein Refseq : | NP_002244 |
MIM : | 191306 |
UniProt ID : | P35968 |
Products Types
◆ Lysates | ||
KDR-1520MCL | Recombinant Mouse KDR cell lysate | +Inquiry |
◆ Assay kits | ||
Kit-1609 | KDR Activity Assay Kit | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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