| Description : |
This gene encodes a member of a family of molecular motors which are involved in intracellular transport of protein complexes, membrane organelles, and messenger ribonucleic acid along microtubules. Kinesins function as homodimeric molecules with two N-terminal head domains that move along microtubules and two C-terminal tail domains that interact with the transported cargo, either directly or indirectly, through adapter molecules. This gene is ubiquitously expressed in coronary arteries and other vascular tissue. A naturally occurring mutation in this gene is associated with coronary heart disease. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
92.4 kDa |
| AA Sequence : |
MVKQTIQIFARVKPPVRKHQQGIYS IDEDEKLIPSLEIILPRDLADGFVN NKRESYKFKFQRIFDQDANQETVFE NIAKPVAGSVLAGYNGTIFAYGQTG SGKTFTITGGAERYSDRGIIPRTLS YIFEQLQKDSSKIYTTHISYLEIYN ECGYDLLDPRHEASSLEDLPKVTIL EDPDQNIHLKNLTLHQATTEEEALN LLFLGDTNRMIAETPMNQASTRSHC IFTIHLSSKEPGSATVRHAKLHLVD LAGSERVAKTGVGGHLLTEAKYINL SLHYLEQVIIALSEKHRSHIPYRNS MMTSVLRDSLGGNCMTTMIATLSLE KRNLDESISTCRFAQRVALIKNEAV LNEEINPRLVIKRLQKEIQELKDEL AMVTGEQRTEALTEAELLQLEKLIT SFLEDQDSDSRLEVGADMRKVHHCF HHLKKLLNDKKILENNTVSSESKDQ DCQEPLKEEEYRKLRDILKQRDNEI NILVNMLKKEKKKAQEALHLAGMDR REFRQSQSPPFRLGNPEEGQRMRLS SAPSQAQDFSILGKRSSLLHKKIGM REEMSLGCQEAFEIFKRDHADSVTI DDNKQILKQRFSEAKALGESINEAR SKIGHLKEEITQRHIQQVALGISEN MAVPLMPDQQEEKLRSQLEEEKRRY KTMFTRLKALKVEIEHLQLLMDKAK VKLQKEFEVWWAEEATNLQVNSPAV NSLDHTKPFLQTSDSQHEWSQLLSN KSSGGWEVQDQGTGRFDVCDVNARK ILPSPCPSPHSQKQSSTSTPLEDSI PKRPVSSIPLTGDSQTDSDIIAFIK ARQSILQKQCLGSNTRTRPLEQKLI SEEDLAANDILDYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
