Recombinant Human KIR2DL2 protein, His-Avi-tagged, Biotinylated

• Cat.No.: KIR2DL2-627HB
• Product Overview: Biotinylated Recombinant Human KIR2DL2 Protein is expressed from mammalian with His Tag and Avi Tag at the C-terminal. It contains His22-His245.

Specification

• Species: Human
• Source: HEK293
• Tag: Avi&His
• Protein Length: His22-His245
• Description: KIR2DL2 (2DL2, formerly NKAT6, designated CD158b) is a 348 amino acid (aa) type I transmembrane glycoprotein that belongs to the human killer cell Ig‑like receptor (KIR) family. KIRs are expressed on human CD56dim NK cells and T cell subsets, and regulate effector functions in the innate immune system.KIR2DL2 is receptor on natural killer (NK) cells for HLA-Cw1, 3, 7, and 8 allotypes. Inhibits the activity of NK cells thus preventing cell lysis.
• Form: Supplied as 0.22um filtered solution in PBS (pH 7.4).
• Molecular Mass: The protein has a predicted MW of 27.4 KDa. Due to glycosylation, the protein migrates to 45-60 KDa based on Bis-Tris PAGE result.
• Endotoxin: Less than 0.1 EU per ug by the LAL method.
• Purity: > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
• Storage: The product should be stored at -70°C. Please do not repeated freeze-thaw cycles.
• Conjugation: Biotin

Gene Information

• Gene Name: KIR2DL2
• Official Symbol: KIR2DL2
• Synonyms: AGS2; hN2; neurogenic locus notch homolog protein 2; Notch (Drosophila) homolog 2; notch 2Notch homolog 2 (Drosophila); Notch homolog 2; Notch2; Notch-2
• Gene ID: 3803
• mRNA Refseq: NM_014219.2
• Protein Refseq: NP_055034.2
• UniProt ID: P43627