| Description : |
This gene is a member of the kelch-like family. The encoded protein contains a BACK domain, a BTB/POZ domain, and 5 Kelch repeats. This protein is thought to function in skeletal muscle development and maintenance. Mutations in this gene have been associated with nemaline myopathy (NM), a rare congenital muscle disorder. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
68 kDa |
| AA Sequence : |
MDSQRELAEELRLYQSTLLQDGLKD LLDEKKFIDCTLKAGDKSLPCHRLI LSACSPYFREYFLSEIDEAKKKEVV LDNVDPAILDLIIKYLYSASIDLND GNVQDIFALASRFQIPSVFTVCVSY LQKRLAPGNCLAILRLGLLLDCPRL AISAREFVSDRFVQICKEEDFMQLS PQELISVISNDSLNVEKEEAVFEAV MKWVRTDKENRVKNLSEVFDCIRFR LMTEKYFKDHVEKDDIIKSNPDLQK KIKVLKDAFAGKLPEPSKNAAKTGA GEVNGDVGDEDLLPGYLNDIPRHGM FVKDLILLVNDTAAVAYDPTENECY LTALAEQIPRNHSSIVTQQNQIYVV GGLYVDEENKDQPLQSYFFQLDSIA SEWVGLPPLPSARCLFGLGEVDDKI YVVAGKDLQTEASLDSVLCYDPVAA KWNEVKKLPIKVYGHNVISHKGMIY CLGGKTDDKKCTNRVFIFNPKKGDW KDLAPMKIPRSMFGVAVHKGKIVIA GGVTEDGLSASVEAFDLTTNKWDVM TEFPQERSSISLVSLAGSLYAIGGF AMIQLESKEFAPTEVNDIWKYEDDK KEWAGMLKEIRYASGASCLATRLNL FKLSKLTRTRPLEQKLISEEDLAAN DILDYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
