Recombinant Human KLHL42 Protein, MYC/DDK-tagged, C13 and N15-labeled

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Recombinant Human KLHL42 Protein, MYC/DDK-tagged, C13 and N15-labeled

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Cat.No. : KLHL42-424H
Product Overview : KLHDC5 MS Standard C13 and N15-labeled recombinant protein (NP_065833) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.
Description : Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex required for mitotic progression and cytokinesis. The BCR(KLHL42) E3 ubiquitin ligase complex mediates the ubiquitination and subsequent degradation of KATNA1. Involved in microtubule dynamics throughout mitosis.
Source : HEK293
Species : Human
Tag : Myc/DDK
Molecular Mass : 56.9 kDa
AA Sequence : MSAEEMVQIR LEDRCYPVSK RKLIEQSDYF RALYRSGMRE ALSQEAGGPE VQQLRGLSAP GLRLVLDFIN AGGAREGWLL GPRGEKGGGV DEDEEMDEVS LLSELVEAAS FLQVTSLLQL LLSQVRLNNC LEMYRLAQVY GLPDLQEACL RFMVVHFHEV LCKPQFHLLG SPPQAPGDVS LKQRLREARM TGTPVLVALG DFLGGPLAPH PYQGEPPSML RYEEMTERWF PLANNLPPDL VNVRGYGSAI LDNYLFIVGG YRITSQEISA AHSYNPSTNE WLQVASMNQK RSNFKLVAVN SKLYAIGGQA VSNVECYNPE QDAWNFVAPL PNPLAEFSAC ECKGKIYVIG GYTTRDRNMN ILQYCPSSDM WTLFETCDVH IRKQQMVSVE ETIYIVGGCL HELGPNRRSS QSEDMLTVQS YNTVTRQWLY LKENTSKSGL NLTCALHNDG IYIMSRDVTL STSLEHRVFL KYNIFSDSWE AFRRFPAFGH NLLVSSLYLP NKAETTRTRP LEQKLISEED LAANDILDYK DDDDKV
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 3 months from receipt of products under proper storage and handling conditions.
Storage : Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
Concentration : 50 μg/mL as determined by BCA
Storage Buffer : 100 mM glycine, 25 mM Tris-HCl, pH 7.3.
SDS-PAGE :

Gene Name : KLHL42 kelch like family member 42 [ Homo sapiens (human) ]
Official Symbol : KLHL42
Synonyms : KLHL42; kelch like family member 42; Ctb9; KLHDC5; kelch-like protein 42; cullin-3-binding protein 9; kelch domain containing 5; kelch domain-containing protein 5
Gene ID : 57542
mRNA Refseq : NM_020782
Protein Refseq : NP_065833
MIM : 618919
UniProt ID : Q9P2K6

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