Active Recombinant Human KLK2 protein, His-tagged
Cat.No. : | KLK2-152H |
Product Overview : | Recombinant Human KLK2(Met1-Pro261) fused with His tag at C-terminal was expressed in NS0. |
- Specification
- Gene Information
- Related Products
Description : | Kallikrein 2 (KLK2) is a secreted serine protease that is highly expressed in the human prostate gland. It is also known as the prostate-specific glandular kallikrein. The enzyme is highly specific for cleavage after arginine residues. KLK2 is able to activate the urokinase-type plasminogen activator. KLK2 is inhibited by serpins such as protein C inhibitor, antichymotrypsin, and plasminogen activator inhibitor 1. KLK2 is structurally related to KLK3, the prostate-specific antigen (PSA). Like PSA, KLK2 is considered to be a biomarker for prostate cancer. |
Source : | Mammalian cells |
Species : | Human |
Tag : | His |
Predicted N Terminal : | Ile25 & Leu124 |
Form : | Supplied as a 0.2 μm filtered solution in Sodium Citrate and NaCl. |
Bio-activity : | Measured by its ability to cleave a flourogenic peptide substrate Pro-Phe-Arg-7-amido-4-methylcoumarin (PFR-AMC). The specific activity is >125 pmol/min/μg. |
Molecular Mass : | Predicted Molecular Mass: 28 & 16 kDa;SDS-PAGE: 34 kDa & 15-18 kDa, reducing conditions. |
Endotoxin : | <1.0 EU per 1 μg of the protein by the LAL method. |
Purity : | >85%, by SDS-PAGE under reducing conditions and visualized by Colloidal Coomassie® Blue stain at 5 μg per lane |
Storage : | Avoid repeated freeze-thaw cycles.6 months from date of receipt, -70 centigrade as supplied.3 months, -70 centigrade under sterile conditions after opening. |
Gene Name : | KLK2 kallikrein-related peptidase 2 [ Homo sapiens ] |
Official Symbol : | KLK2 |
Synonyms : | KLK2; kallikrein-related peptidase 2; kallikrein 2, prostatic; kallikrein-2; tissue kallikrein-2; glandular kallikrein 2; glandular kallikrein-1; hK2; hGK-1; KLK2A2; FLJ17010; FLJ17011; MGC12201; |
Gene ID : | 3817 |
mRNA Refseq : | NM_001002231 |
Protein Refseq : | NP_001002231 |
MIM : | 147960 |
UniProt ID : | P20151 |
Chromosome Location : | 19q13.33 |
Pathway : | Activation of Matrix Metalloproteinases, organism-specific biosystem; Coregulation of Androgen receptor activity, organism-specific biosystem; Degradation of the extracellular matrix, organism-specific biosystem; Endocrine and other factor-regulated calcium reabsorption, organism-specific biosystem; Endocrine and other factor-regulated calcium reabsorption, conserved biosystem; Extracellular matrix organization, organism-specific biosystem |
Function : | peptidase activity; serine-type endopeptidase activity; |
Products Types
◆ Recombinant Protein | ||
KLK2-2372H | Recombinant Human KLK2 Protein, His-tagged | +Inquiry |
KLK2-2373H | Recombinant Human KLK2 Protein, His-tagged | +Inquiry |
KLK2-2371H | Recombinant Human KLK2 Protein, His-tagged | +Inquiry |
KLK2-1257H | Recombinant Human KLK2 Protein, His (Fc)-Avi-tagged | +Inquiry |
KLK2-4351H | Recombinant Human KLK2 Protein (Pro19-Pro261), N-His tagged | +Inquiry |
◆ Lysates | ||
KLK2-947HCL | Recombinant Human KLK2 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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