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Recombinant Human KLRC4 Protein, GST-tagged

Cat.No. : KLRC4-4912H
Product Overview : Human KLRC4 full-length ORF ( AAH17784, 1 a.a. - 158 a.a.) recombinant protein with GST-tag at N-terminal.
  • Specification
  • Gene Information
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Description : Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. NK cells preferentially express several calcium-dependent (C-type) lectins, which have been implicated in the regulation of NK cell function. KLRC4 is a member of the NKG2 group which are expressed primarily in natural killer (NK) cells and encodes a family of transmembrane proteins characterized by a type II membrane orientation (extracellular C terminus) and the presence of a C-type lectin domain. The NKG2 gene family is located within the NK complex, a region that contains several C-type lectin genes preferentially expressed on NK cells. The 3 end of the KLRC4 transcript includes the first non-coding exon found at the 5 end of the adjacent D12S2489E gene transcript. [provided by RefSeq
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 43.12 kDa
AA Sequence : MNKQRGTYSEVSLAQDPKRQQRKLK GNKISISGTKQEIFQVELNLQNASS DHQGNDKTYHCKGLLPPPEKLTAEV LGIICIVLMATVLKTIVLIPCIGVL EQNNFSLNRRMQKARHCGHCPEEWI TYSNSCYYIGKERRTWEERVCWPVL RRTLICFL
Applications : Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Gene Name : KLRC4 killer cell lectin-like receptor subfamily C, member 4 [ Homo sapiens ]
Official Symbol : KLRC4
Synonyms : KLRC4; killer cell lectin-like receptor subfamily C, member 4; NKG2-F type II integral membrane protein; NKG2 F; NK cell receptor F; natual killer cell group 2-F; NKG2-F-activating NK receptor; NKG2F; NKG2-F; FLJ17759; FLJ78582;
Gene ID : 8302
mRNA Refseq : NM_013431
Protein Refseq : NP_038459
MIM : 602893
UniProt ID : O43908

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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