Recombinant Human KMT2C Complex, His-tagged

• Cat.No.: KMT2C-130H
• Product Overview: Recombinant Human MLL3 (4689-4911), WDR5 (22-334), RbBP5 (1-538), Ash2L (2-534), DPY-30 (1-99) protein, fused with N-terminal His-tag on all subunits, was expressed in E.coli.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 4689-4911;22-334;1-538;2-534;1-99 a.a.
• Form: 20 mM Tris-HCl, pH 7.5, 300 mM NaCl, 1 mM TCEP (tris(2-carboxyethyl)phosphine HCl), 10% (w/v) glycerol, 1 µM ZnCl2.
• Molecular Mass: 211.0 kDa
• Purity: >90% by SDS-PAGE
• Storage: Store at -80°C. Thaw quickly and store on ice before use. Avoid repeated freezing and thawing cycles.

Gene Information

• Gene Name: KMT2C lysine (K)-specific methyltransferase 2C [ Homo sapiens ]
• Official Symbol: KMT2C
• Synonyms: HALR; MLL3; ALR-like protein; histone-lysine N-methyltransferase MLL3; histone-lysine N-methyltransferase, H3 lysine-4 specifichomologous to ALR protein; myeloid/lymphoid or mixed-lineage leukemia protein 3
• Gene ID: 58508
• mRNA Refseq: NM_170606
• Protein Refseq: NP_733751
• MIM: 606833
• UniProt ID: Q8NEZ4
• Chromosome Location: 7q36.1
• Pathway: Chromatin modifying enzymes, organism-specific biosystem; Lysine degradation, organism-specific biosystem; PKMTs methylate histone lysines, organism-specific biosystem
• Function: DNA binding; poly(A) RNA binding; zinc ion binding