Recombinant Human KMT2D Protein (H5382-M5536), GST tagged

• Cat.No.: KMT2D-0540H
• Product Overview: Recombinant Human GST-TEV-(GG)-KMT2D(H5382-M5536) Protein was expressed in E. coli.

Specification

• Species: Human
• Source: E.coli
• Tag: GST
• Protein Length: H5382-M5536
• Description: Histone methyltransferase that catalyzes methyl group transfer from S-adenosyl-L-methionine to the epsilon-amino group of 'Lys-4' of histone H3 (H3K4). Part of chromatin remodeling machinery predominantly forms H3K4me1 methylation marks at active chromatin sites where transcription and DNA repair take place. Acts as a coactivator for estrogen receptor by being recruited by ESR1, thereby activating transcription.
• Form: Liquid
• Endotoxin: < 0.01 EU per μg of the protein
• Purity: 90%
• Stability: Samples are stable for up to twelve months from date of receipt at -20 to -80 centigrade.
• Storage: Store it under sterile conditions at -20 to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Storage Buffer: Supplied as sterile 50mM Tris-HCl (pH 7.5), 200mM NaCl, 20% glycerol
• Shipping: It is shipped out with blue ice.

Gene Information

• Gene Name: KMT2D lysine methyltransferase 2D [ Homo sapiens (human) ]
• Official Symbol: KMT2D
• Synonyms: KMT2D; lysine methyltransferase 2D; ALR; KMS; MLL2; MLL4; AAD10; BCAHH; KABUK1; TNRC21; CAGL114; histone-lysine N-methyltransferase 2D; ALL1-related protein; Kabuki make-up syndrome; histone-lysine N-methyltransferase MLL2; lysine (K)-specific methyltransferase 2D; lysine N-methyltransferase 2D; myeloid/lymphoid or mixed-lineage leukemia 2; trinucleotide repeat containing 21; EC 2.1.1.364
• Gene ID: 8085
• mRNA Refseq: NM_003482
• Protein Refseq: NP_003473
• MIM: 602113
• UniProt ID: O14686