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Recombinant Human KNG1 Protein

Cat.No. : KNG1-049H
Product Overview : Recombinant protein of human kininogen 1 (KNG1)(Gln19-Ser427), transcript variant 2, was expressed in HEK293 cells.
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Description : This gene uses alternative splicing to generate two different proteins- high molecular weight kininogen (HMWK) and low molecular weight kininogen (LMWK). HMWK is essential for blood coagulation and assembly of the kallikrein-kinin system. Also, bradykinin, a peptide causing numerous physiological effects, is released from HMWK. Bradykinin also functions as an antimicrobial peptide with antibacterial and antifungal activity. In contrast to HMWK, LMWK is not involved in blood coagulation. Three transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Nov 2014]
Source : HEK293 cell
Species : Human
Molecular Mass : 46.9 kDa
Endotoxin : < 0.1 EU per µg protein as determined by LAL test.
Purity : > 95% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for at least 6 months from date of receipt under proper storage and handling conditions.
Concentration : Resuspend the protein to the desired concentration in proper buffer.
Storage Buffer : Lyophilized from a 0.2 µM filtered solution of 20mM Hac-NaAC, 150mM NaCl, pH 4.0.
Gene Name : KNG1 kininogen 1 [ Homo sapiens ]
Official Symbol : KNG1
Synonyms : KNG1; kininogen 1; BDK, kininogen, KNG; kininogen-1; alpha 2 thiol proteinase inhibitor; bradykinin; HMWK; fitzgerald factor; high molecular weight kininogen; alpha-2-thiol proteinase inhibitor; williams-Fitzgerald-Flaujeac factor; BDK; KNG;
Gene ID : 3827
mRNA Refseq : NM_000893
Protein Refseq : NP_000884
MIM : 612358
UniProt ID : P01042

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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07/26/2021

    Utilizing protein reagents reduces material consumption in experiments, resulting in resource conservation.

    05/09/2019

      The usage method of protein reagents is flexible, adapting to various experimental requirements.

      01/06/2018

        The precise and reliable results achieved by employing protein reagents make them highly favored in scientific research.

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